The Croucher Advanced Study Institute on
“Molecular Genetics and Cell Signaling in Cancer and Cancer Metastasis”
Professor Sara A Courtneidge
Cell Adhesion and Extracellular Matrix Biology,
The Burnham Institute, USA
Topic 1: Therapeutic Targeting of Kinases for Cancer Therapy: Progress and Promise
Topic 2: The Control of Proteolytic Activity in Cancer Cells
Professor Scott W Lowe
Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, USA
Topic 1: Genetics of Drug Sensitivity and Resistance in Cancer
Topic 2: Dissecting the p53 Tumor Suppressor Gene Network Using Mouse Models and RNA Interference
Professor Randall T Moon
Howard Hughes Medical Institute, Department of Pharmacology, University of Washington, USA
Topic 1: Wnt/beta Catenin Signaling, Cancer, and Therapies
Topic 2: Noncanonical Wnt Signaling, Cancer, and Metastasis
Professor Charles J Sherr
Howard Hughes Medical Institute, Department of Genetics and Tumor Cell Biology,
St Jude Children's Research Hospital, USA
Topic 1: The ARF Tumor Suppressor
Topic 2: CDK Inhibitors and Cancer
Professor Frank J Slack
Cellular and Developmental Biology,
Yale University, USA
Topic 1: MicroRNAs in Cell Differentiation and Cancer
Topic 2: The Let-7 MicroRNA Regulates Cell Cycle Oncogenes
29 January - 2 February 2007
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