A Seminar MicroRNA Profiling of Gastric CancerbyDr Chan April Sheila 1:00 pm, Thursday, 24 May 2018 |
A Seminar Functional Genomic and Epigenetic Landscapes of Liver Cancer by Dr Wong Chun Ming, Jack 1:00 pm, Thursday, 24 May 2018 |
A Seminar Characterization of by Dr Chan Lo Kong 1:00 pm, Thursday, 29 March2018 |
For information and online registration, please click here. |
A Seminar The Role of Cripto-1 in Hepatocellular Carcinoma by Dr Regina Lo 1:00 pm, Thursday, 8 February 2018 |
A Seminar Understanding the Transcriptional Regulation of HBV Replication by Dr Sze Man Fong, Karen 1:00 pm, Thursday, 1 February 2018 |
A Seminar mTOR Inhibition Combined with Phenformin in Hepatocellular Carcinoma Management by Dr Xuemei Ge Post-doctoral Fellow 1:00 PM, Thursday, 7 December 2017 |
A Seminar Signal Cross-Talks in Leukemia, Anemia and Liver Cancer by Professor Gen-Sheng Feng Professor of Pathology and Molecular Biology 1:00 pm, 1 December 2017 |
Jointly organized by A Seminar GATA4 – a Transcription Factor Beyond a Differentiation Driver in Liver by Dr Timothy Wai Ho Shuen Research Fellow 1:00 pm, Thursday, 16 November 2017 |
On-line registration, please Click here |
A Seminar by Dr Lai Chun Cheong Jimmy 1:00 pm, Thursday, 9 November 2017 |
A Technology Seminar |
A Seminar Watching the Great Myeloid Cell Migration HKCPath - 1 CME point |
A Seminar Immune Cell Fractions Analysis in Gastric Cancer HKCPath - 1 CME point |
A Seminar Frequent TERT Genomic Alterations in HKCPath - 1 CME point |
A Seminar Are We Missing Myelofibrosis? A Review of Prefibrotic MF HKCPath - 1 CME point |
A Seminar Molecular Pathology and the Pathology Curriculum HKCPath - 1 CME point |
A Seminar Caveolin-1, A Cancer Metastasis Promoter in Liver Cancer by Dr Judy Yam 1:00 pm, Thursday, 31 August 2017 MLT CPD code: 04171041 |
Click here for program and registration form |
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Endocrine Pathology Update in 2017: by Professor Hironobu Sasano 4:00 pm, Thursday, 8 Jun 2017 MLT CPD code: 04171031 |
A Seminar In Search of Molecular Targets of Ovarian Cancer by Dr Wong Gee Wan, Oscar 1:00 pm, Thursday, 11 May 2017 MLT CPD code: 04171011 |
A Seminar Dishevelled-3 Phosphorylation Governed by HIPK2/PP1Cα/ITCH Axis Mediates Cancer Stemness via LGR5 in Liver Cancer by Dr Yu-Man Tsui 1:00 pm, Thursday, 6 April 2017 |
Seminar I (4:00pm – 5:00pm) Liver Fibrosis - Pathology and Pathogenesis Seminar II (5:00pm – 6:00pm) Approach to Hepatocellular Nodules including Immunohistochemistry by Dr Andrew Clouston 4:00 – 6:15 PM, Thursday, March 30, 2017 |
A Seminar Targeting of Super-enhancer Associated Oncogenes in Hepatocellular Carcinoma by Dr Felice Tsang 1:00 pm, Thursday, 23 March 2017 |
A Seminar Proteomic Profiling of Gastrointestinal Cancers by Dr Helen Yan 1:00 pm, Thursday, 9 March 2017 MLT CPD code: 04161221 |
Jointly organized by A Seminar by Dr Keane Lai 1:00 PM, Thursday, 23 February 2017 |
A Seminar by Dr Alberto Quaglia 1:00 PM, Thursday, 9 February 2017 |
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A Seminar by Dr Mao Xiaowen, Susan 1:00 PM, Thursday, 1 December 2016 |
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A Seminar by Dr Carmen Leung 1:00 PM, Thursday, 24 November 2016 |
A Seminar by Professor W. John Kao 1:00 PM, Wednesday, 23 November 2016 |
A Seminar by Dr Philip SL Beh 1:00 PM, Thursday, 13 October 2016 |
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A Seminar by Dr Alan S.L. Wong 1:00 PM, Thursday, 29 September 2016 |
Jointly organized by
A Seminar by Dr Sanjiv Manek 5:00 – 6:00 PM, Monday, September 5, 2016 |
Jointly organized
A Seminar by Professor Wendy Erber 6:00 PM, Monday, 29 August 2016 |
A Seminar by Dr. Victoria Perrier-Trudova 1:00 PM, Thursday, 25 August 2016 |
A Seminar Whole-genome Sequencing and Comprehensive Molecular Profiling of Gastric Cancer by Professor Leung Suet-yi 1:00 PM, Thursday, 4 August 2016 |
A Seminar Role of CLEC16A in Autoimmunity by Dr Vera Sau-fong Chan 1:00 PM, Thursday, 28 July 2016 |
A Seminar An Integrated Analysis of the Human Gastric Cancer Methylome by Dr April Sheila Chan 1:00 PM, Thursday, 14 July 2016 |
You are invited to attend a lecture by Professor Hans Clevers, Senior group leader of the Hubrecht Institute of Developmental Biology and Stem Cell Research in University of Utrecht and Scientific Director of the Princess Máxima Center for Pediatric Oncology http://www.hubrecht.eu/onderzoekers/clevers-group/, who has recently been appointed as Distinguished Visiting Scholar in the Medical Faculty. Title: Lgr5 stem cell-grown organoids and their applications The lecture is jointly organised by the Medical Faculty, Stem Cell and Regenerative Medicine Consortium and Department of Pathology. ALL ARE WELCOME |
A Seminar Intronic Hepatitis B Virus (HBV) Integration Generates Viral-host Chimera by Dr Chiu Yung Tuen, Elley 1:00 PM, Thursday, 23 June 2016 |
A Seminar The Role of Epigenetics in Cancer Mutagensis by Dr Benjamin Schuster-Böckler 4:00 PM, Wednesday, 22 June 2016 |
Seminar I Single Cell RNA Sequencing Wanda Yen-Wen Li Seminar II Cancer Drugs Development in Academia: Is it Realistic? Professor Tak Wah Mak 3:00 PM - 5:00 PM, Tuesday, 14 June 2016 |
A Seminar The Evolution of Laboratory Assessment of Myeloproliferative Neoplasms by Dr Jason So 1:00 PM, Thursday, 26 May 2016 |
A Seminar Genetic Testing for Colon Cancer: Hope, Hype and Reality by Professor Nicholas O. Davidson 5:00 PM, Wednesday, 27 April 2016 |
A Seminar New Insights into Pathways Linking Lipid Metabolism and Liver Injury by Professor Nicholas O. Davidson 5:00 PM, Tuesday, 26 April 2016 |
A Seminar Role of Transcription Factor MYBL2 in Hepatocellular Carcinoma by Dr Sze Man Fong, Karen 1:00 PM, Thursday, 21 April 2016 |
A Seminar Roles of Innate B cells in Infection and Autoimmunity by Professor Liwei Lu 1:00 PM, Thursday, 7 April 2016 |
Jointly organized by A Seminar Murine and Human Hematopoietic Stem Cells in Chronic Inflammation by Dr Lisa Ann Borghesi 1:00 PM, Friday, 1 April 2016 |
A Seminar DLC1 regulates beta-oxidation genes by Dr Ko Chi Fat, Frankie 1:00PM, Thursday, 31 March 2016 |
A Seminar Drug Discovery Partnership with Biotech/Pharmaceutical Industry by Professor John Luk 1:00PM, Tuesday, 15 March 2016 |
A Seminar Studies on the Immunopathogenesis of Sjögren’s Syndrome by Dr Alex Xiang LIN 1:00PM, Thursday, 3 March 2016 |
A Seminar Molecular Perspectives of Rare Epithelial Ovarian Tumors and Therapeutic Implication by Professor Kwong-Kwok Wong 1:00PM, Thursday, 25 February 2016 |
A Seminar Dosage and Phenotype in
Down Syndrome by Professor Cheung Nga Yin, Annie 1:00PM, Thursday, 18 February 2016 |
Click here to download event program |
A Seminar Identification and characterization of recurrent gene mutations in HBV-associated HCC by exome and targeted sequencing by Dr Chan Lo Kong 1:00 PM, Thursday, 10 December 2015 |
Jointly organized by
A Seminar A B-Cell Biography by Professor Dennis G. Osmond 4:00- 5:00PM, Wednesday, 11 November 2015 |
A Seminar Undiagnosed Diseases Program by Professor Ching-Wan Lam 1:00 PM, Thursday, 15 October 2015 |
A Seminar Viral Integration Detection in Cancer by Dr Daniel Wai Hung HO 1:00 PM, Thursday, 8 October 2015 |
A Seminar The Role of Autophagy in Ovarian Clear Cell Carcinoma by Dr Chan Ka Kui 1:00 PM, Thursday, September 17, 2015 |
A Seminar Large Scale Study for NGS Data of Gastric Cancer by Dr Siu Hoi Cheong 1:00 PM, Thursday, August 20, 2015 |
A Seminar Making Sense of Blood by Professor Li-Chong Chan 1:00 PM, Thursday, July 23, 2015 |
A Seminar Application of Whole Exome Sequencing in Metachronous Lung Cancer Evaluation By Dr Maria Wong 1:00 PM, Thursday, July 16, 2015 |
A Seminar Hepatocellular Carcinoma – Updates in Molecular Pathogenesis by Professor Irene Oi-Lin Ng 1:00 PM, Thursday, July 9, 2015 |
A Seminar Autoimmuno-Anti-Tumour Immunity (AATI) – Understanding the Immune Responses against “Self” & “Altered-self” by Dr Huang Fang-Ping 1:00 PM, Thursday, June 18, 2015 |
A Seminar Applications of Gastrointestinal Organoid Cultures: from Cancer Biology to Clinical Study by Dr Yan Hoi Ning, Helen 1:00 PM, Thursday, May 21, 2015 |
A Seminar The Role of Nuclear Met by Dr Yam Wai Ping, Judy 1:00 PM, Thursday, May 14, 2015 |
A Seminar The Role of PIM1 in Hepatocellular Carcinoma by Dr Lo Cheuk Lam, Regina 1:00 PM, Thursday, April 23, 2015 |
A Seminar How to Find Patients with by Hudson Freeze, Ph.D 3:30 PM, Wednesday, April 22, 2015 |
A Seminar Translational Diagnostic Medicine: by Dr Law Chun Yiu, Eric 1:00 PM, Thursday, April 16, 2015 All are welcome |
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A Seminar Cytopathology of Pancreatic Lesions by Professor Syed Z. Ali 1:00 PM, Thursday, March 12, 2015 **Light refreshment will be provided** |
A Slide Seminar Interesting Cases from by Dr Cheung Man Fung, Florence 1:00 PM, Wednesday, February 25, 2015 |
Click here to download event program |
The Surgical Pathology of Lipomatous Tumors by Professor Brian Rubin 1:00 PM, Thursday, February 5, 2015
All are welcome |
A Seminar Where Have All The Thalassaemias Gone? by Dr So Chi-Chiu, Jason 1:00 PM, Thursday, January 29, 2015
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A Seminar Novel Pre-mRNA Splicing of Intronic Integrated HBV by Dr Chiu Yung Tuen, Elley 1:00 PM, Thursday, January 22, 2015 |
A Seminar Renal Biopsies at QMH – by Dr Chan Kwok Wah 1:00 PM, Thursday, December 18, 2014 |
A Seminar Roles of B Cells in Autoimmunity by Professor Liwei Lu 1:00 PM, Thursday, December 4, 2014 |
A Seminar The Stories of by Dr Chan Sau Fong Vera 1:00 PM, Thursday, November 27, 2014 |
(Cancelled) Jointly organized by Department of Pathology A Seminar A B-Cell Biography by Professor Dennis G. Osmond 4:00 - 5:00 PM, Thursday, November 6, 2014 (Cancelled) All are welcome |
A Seminar Deregulation of by Dr Sze Man Fong Karen 1:00 PM, Thursday, October 30, 2014 |
A Seminar Autoimmune Bullous Diseases: by Dr May Chan 1:00 PM, Thursday, October 23, 2014 All are welcome |
Jointly organized by Department of Pathology A Seminar Cancer Cell by Dr. Li-Kuo Su 3:30 - 4:30 PM, Wednesday, October 15, 2014 All are welcome |
A Seminar The Power of Eternal Youth – by Professor Annie Cheung 1:00 PM, Thursday, September 18, 2014 All are welcome |
A Seminar New Insights by Professor John Nicholls 1:00 PM, Thursday, September 4, 2014 All are welcome |
A Seminar Deleted in Liver Cancer 1 (DLC1) by Dr Ko Chi Fat, Frankie 1:00 PM, Thursday, August 28, 2014 All are welcome |
A Seminar Targeting CD47 as a Novel Therapeutic Strategy by Dr Lee Kin Wah, Terence 1:00 PM, Thursday, August 21, 2014 All are welcome |
A Seminar Deregulation of Epigenetic Modifying Enzymes in Liver Cancer by Dr Wong Chun Ming, Jack 1:00 PM, Thursday, July 31, 2014 All are welcome |
A Seminar Application of Whole-Exome Sequencing by Dr Lai Chun Wan, Jeffrey 1:00 PM, Thursday, June 26, 2014 |
A Seminar Molecular Target Discovery in by Dr Wong Gee Wan, Oscar 1:00 PM, Thursday, June 12, 2014 |
A Seminar Role of MicroRNA-135a by Dr Leung Oi Ning, Carmen 1:00 PM, Thursday, May 29, 2014 |
A Seminar A Critical Role of Th17 Cells by Dr Lin Xiang 1:00 PM, Thursday, May 22, 2014 |
A Seminar The Functional Role of by Dr Chan Lo Kong 1:00 PM, Thursday, April 24, 2014 |
A Seminar Human Metabolic Phenotyping by Professor Lam Ching Wan 1:00 PM, Thursday, April 17, 2014 |
A Seminar CamKII Mediates the Tumor-initiating by Dr Liu Jing, Emily 1:00 PM, Thursday, March 27, 2014 |
Jointly organized by Technology Seminar Resolution of Biological Lipid Extracts by Paul RS Baker, PhD March 26, 2014 (Wed) Advances in this mass spectrometry have enabled in-depth lipidomic analysis with unparalleled quantitative sensitivity. However, unambiguous identification and quantitation of lipid molecular species in total lipid extracts is difficult due to extensive isobaric interference. There are greater than 100,000 lipid molecular species present in a typical biological lipid extract that occupy a narrow mass range (~400-1100 amu), making isobaric overlap a significant problem. Currently, this problem is addressed by time-consuming, complex chromatography, including fractionation, 2-D LC strategies and chiral chromatographic columns. An alternative to chromatography has become available with the advent of SelexIONTM technology, which separates molecules based on their differential ion mobility in an oscillating electrical field prior to analysis by mass spectrometry. This technique resolves molecules by chemical effects and offers a method to analyze lipids in a unique and comprehensive way. |
Jointly organized by Department of Pathology and A Seminar From Cell Death to Sudden Death: by Abstract: Molecules that maintain normal cardiac function through p53-dependent and -independent pathways are potential targets of chemotherapy-induced cardiotoxicity. Here, we identify iASPP, an inhibitor of p53, as one such candidate. iASPP deficiency-causing spontaneous mutations are associated with cardiocutaneous disorders in CWH calves and Wa3 mice. In humans, cardiocutaneous disorder often associates with desmosomal dysfunction. We show here that iASPP deficiency specifically induces apoptosis and right ventricular dilation in E16.5 mouse embryos. iASPPΔ8/Δ8 mice die of sudden death, displaying features of Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC). iASPP deficiency causing excessive cardiomyocyte loss was largely rescued in iASPPΔ8/Δ8;p53-/- hearts. Moreover, iASPP anchors desmoplakin and desmin at the intercalated discs and binds desmoplakin, forming a trimeric complex with desmin or keratin to maintain the integrity of desmomsomes and intermediate filament networks in cardiomyocytes and keratinocytes, respectively. iASPP, therefore, prevents cardiocutaneous disorder through its ability to inhibit p53-induced apoptosis and maintain desmosome function. |
A Seminar Tumor Microenvironment: by Dr Wong Chak Lui, Carmen 1:00 PM, Thursday, March 13, 2014 |
A Seminar Study of Virus-host Receptor Interactions Using Pseudotyped Virus by Dr Lai Chun Cheong, Jimmy 1:00 PM, Thursday, March 6, 2014 |
A Seminar Applicability of Whole Genome Amplified DNA by Dr Ho Wai Hung, Daniel |
A Seminar Unraveling the Genetic Causes of Lymphoma by Sandeep Dave, MD, MS 5:00 PM, Wednesday, February 19, 2014 Research Statement High-throughput technologies will transform the way we diagnose and treat malignancies. Leukemias and lymphomas are malignancies that arise from immune cells. The majority of these malignancies arise from B cells, a type of immune cell. Leukemias and lymphomas derived from B cells affect over 100,000 Americans every year. The majority of those patients will succumb to their disease. Dr. Dave's research is focused on the application of high-throughput technologies including microarrays and massively parallel sequencing to improve the diagnosis and treatment of leukemias and lymphomas. Active efforts in the laboratory and clinic include: 1. Integrating genomic technologies with clinical trials to define molecular subgroups of patients who are most likely to respond to therapy. |
Click here for event photos Click here to download event program |
A Seminar Molecular Features of Ovarian Clear Cell Carcinoma and its Chemoresistance by Dr Chan Ka Kui 1:00 PM, Thursday, January 16, 2014 |
A Seminar Imbalance of FOXP1 Isoforms in Diffuse Large B-cell Lymphoma by Dr Mak Chun Yin, Victor 1:00 PM, Thursday, December 19, 2013 |
A Seminar Role and Regulation of the FOXO3a by Professor Eric WF Lam 4:00 PM, Friday, November 29, 2013 All are welcome |
A Seminar Newborn Screening from Agar to Hightech By Professor Ralph Fingerhut, PhD University Children’s Hospital, Date: 25 November 2013 Time: 2:00 pm – 3:00 pm Venue: All are welcome |
Free Registration -
All Are Welcome |
A Seminar Identifying Novel Key Cancer Regulators by Jun Zhu, Ph.D. 12:00 Noon, Monday, November 11, 2013 Dr. Jun Zhu is a professor in the Department of Genetics and Genomic Sciences, and Director of the Integrative Network Biology Group at the Institute of Genomics and Multiscale Biology, a member of The Tisch Cancer Institute at Icahn School of Medicine at Mount Sinai. Dr. Zhu’s research focuses on developing novel methods for integrating diverse high-throughput data into predictive network models and applying integrative network approaches to understand mechanisms underlying complex human diseases. Being trained in both computer science and biomedical science, Dr. Zhu has a track record of doing innovative biomedical research and providing leadership in the field of systems biology. He has pioneered the integration of genetic and gene expression data into causal networks, which was viewed as “the first to integrate expression QTL data and phenotypic correlation data into causal modelling, as well as to describe the crucial role of genetic perturbations in anchoring causal links in the Bayesian network“ (by Rockman, MV, Nature, 2008). Before joining Mount Sinai School of Medicine, he was a computational biologist at Amgen, Inc (the world largest biotechnology company), then a research fellow and an associate scientific director at Merck & CO (the world second largest pharmaceutical company). After l2 years in biotech industry, he moved to academia. He was a director at Sage Bionetworks, a not-for profit research institute, an affiliate member of Fred Hutchinson Cancer Research Center. Dr. Zhu obtained Bachelor of Engineering in Electronic Engineering from Tsinghua University in Beijing, Master of Computer Sciences and Ph.D in Biomedical Sciences from New York State University at Albany. |
A Seminar Novel miRNA Regulatory Pathways by Professor Victor A Tron 1:00 PM, Tuesday, November 5, 2013 |
Jointly organized by Department of Pathology A Seminar Role of Pak4 in Cancer Progression by Professor Staffan Stromblad 1:00 PM, Thursday, October 31, 2013 All are welcome |
A Seminar Gene Expression under the Microscope by Professor John E.J. Rasko 1:00 PM, Wednesday, October 2, 2013 All are welcome This event is supported by the Visiting Lectureship of the |
A Seminar Understanding Ourselves and Our Patients: by Professor Chan Li Chong 1:00 PM, Thursday, September 26, 2013 All are welcome |
A Seminar Metabolomic Investigations of Infected Urine by Dr Law Chun Yiu, Eric 1:00 PM, Thursday, September 19, 2013 All are welcome |
A Seminar An Update on by Dr Yan Hoi Ning, Helen 1:00 PM, Thursday, September 5, 2013 All are welcome |
A Seminar Tumour - Initiating Cells in Lung Cancer by Dr Wong Pik, Maria 1:00 PM, Thursday, August 29, 2013 All are welcome |
A Seminar Sleeping Beauty Transposon System: by Dr Vincent Keng 1:00 PM, Thursday, August 22, 2013 |
Download detail program here |
The Inaugural Croucher Summer Course in Cancer Biology will be held from 14 - 18 August 2013 (Wed-Sun). It is a five-day residential summer course which aims to educate and inspire talented postdoctoral fellows and early career researchers from Hong Kong and overseas. Applications from promising research postgraduate students would also be considered. World-renowned international and local speakers will conduct seminars and engage in interactive discussions with participants. The Summer Course provides an excellent opportunity for junior scientists to learn from experienced scientists directly. Director: Co-Director: Organized by: Organizing Committee: Chairperson: Members: Sponsored by: Co-sponsored by: Official language: Deadline for Application: Secretariat:
Ms Selina Lam Up-to-date information is available from the Course website http://www.patho.hku.hk/events/croucher/crouchersc/2013 |
A Seminar Receptor Tyrosine Phosphatase PTPRK Directly Targets STAT3 Phosphorylation by Dr Chen Yun Wen, Wendy 1:00 PM, Thursday, July 25, 2013 All are welcome |
A Seminar Post-translational Regulation of DLC1 Tumor Suppressor by Dr Yam Wai Ping, Judy 1:00 PM, Thursday, July 18, 2013 All are welcome |
A Seminar An Update on Histopathology in the Diagnosis of Liver Diseases by Dr Lo Cheuk Lam, Regina 1:00 PM, Thursday, July 11, 2013 All are welcome |
A Seminar "Shaken Baby Syndrome" Recent Developments by Dr CM Milroy Forensic Pathologist 1:00 PM, Wednesday, July 3, 2013 All are welcome |
A Seminar All Out of Breath by Dr Beh Swan Lip, Philip 1:00 PM, Thursday, June 20, 2013 All are welcome |
A Seminar The Roles of Androgen Receptor Signaling in Tumorigenesis by Dr Chiu Yung Tuen, Elley 1:00 PM, Thursday, June 13, 2013 All are welcome |
A Seminar High Resolution Melting Analysis in Haematological Diagnosis by Dr So Chi Chiu, Jason 1:00 PM, Thursday, May 2, 2013 All are welcome |
A Seminar Prognostic Markers by Dr Chan Kwok Wah 1:00 PM, Thursday, April 25, 2013 All are welcome |
A Seminar C-Terminal Truncated HBx Is Associated by Dr Sze Man Fong, Karen 1:00 PM, Thursday, April 11, 2013 All are welcome |
A Seminar Plasmacytoid Dendritic Cells in Systemic Lupus Erythematosus by Dr Chan Sau Fong, Vera 1:00 PM, Thursday, March 28, 2013 All are welcome |
A Seminar Regulation of Oxidative Stress in Infections and Cancer by Professor Tak Mak, F.R.S.C., F.R.S. Visiting Research Professor All are welcome |
A Seminar Roles of Leptin in Immunity and Autoimmunity by Professor Liwei Lu 1:00 PM, Thursday, March 14, 2013 All are welcome |
A Seminar Genomics Study of Gastric Cancer by Professor Leung Suet Yi 1:00 PM, Thursday, February 28, 2013 All are welcome MLT CPD code: 04121241 |
A Seminar Deleted in Liver Cancer 1 (DLC1) Regulates Cancer Metastasis by Dr Ko Chi Fat, Frankie 1:00 PM, Thursday, January 31, 2013 All are welcome |
Jointly organized by Hong Kong Society for Histocompatibility and Immunogenetics and Department of Pathology Scientific seminar HLA & Personalized Medicine by Professor Dominique Charron |
A Seminar Novel Splice Variant of NCOR2 and by Professor Khoo Ui Soon 1:00 PM, Thursday, January 17, 2013 All are welcome |
A Seminar Liver Cancer Stem Cells: by Dr Lee Kin Wah, Terence 1:00 PM, Thursday, December 27, 2012 All are welcome |
A Seminar New Insights in Mutations and Pathogenesis of Burkitt Lymphoma by |
Message from Department of Pathology A Seminar Molecular Regulation of Thrombopoiesis by Professor Beng Chong Visiting Professor 12:30 PM, Tuesday, November 27, 2012 All are welcome MLT CPD code: 04121171 |
A Seminar Lance Armstrong, Global Warming and Influenza Virus Infection by Professor John Nicholls |
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October 31- November 2, 2012 Jointly Organised by and KATHARINE DORMANDY HAEMOPHILIA CENTRE |
A Seminar Aberrant Epigenetic Regulations in MLL-rearranged Leukaemia by Dr Ray Ng |
A Seminar The role of TNF in immune modulations by Professor Tak Mak Professor, Department of Medical Biophysics & All are welcome
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A Seminar Interplay Between Epigenetic and MicroRNA Deregulations by Dr Wong Chun Ming, Jack 1:00 PM, Thursday, September 27, 2012 |
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A Seminar Dysregulation of miR-143 in Cervical Cancer Dr Wong Gee Wan, Oscar |
A Seminar Molecular Genetics of Autism by Professor Lam Ching Wan 1:00 PM, Thursday, August 23, 2012 All are welcome |
A Seminar About the speaker: Charles completed his PhD in 1998 at the Imperial Cancer Research Fund Laboratories on the UCL MBPhD programme before completing his medical oncology and CR-UK funded post-doctoral clinician scientist training in 2008. Charles was appointed Medical Research Council and Cancer Research UK senior clinical research fellow and Group Leader of the Translational Cancer Therapeutics laboratory at the CR-UK London Research Institute in 2008 focussing on personalised cancer medicine through an understanding of mechanisms of drug resistance, intratumour heterogeneity and genomic instability. He combines his laboratory research with clinical duties focussed on drug development in lung and breast cancer. Charles worked as a consultant medical oncologist at the Royal Marsden Hospital with an interest in early phase drug development for the treatment of specific subtypes of metastatic solid tumours (2008-2011). Charles has over 60 publications in peer-reviewed journals including lead or corresponding author papers in Nature, Cancer Cell, PNAS, Lancet Oncology and The New England Journal of Medicine. Charles is a member of several translational research scientific committees including AICR and CR-UK BIDD. He was made Fellow of the Royal College of Physicians in April All are welcome |
A Seminar Dr Tung Kwok Kwan, Edmund |
A Seminar Conquering a Foreign Land: by Dr Wong Chak Lui, Carmen All are welcome |
A Seminar Future Anti-Cancer Targets: Put the Carts Before the Horses? by Professor Tak Mak 4:00 PM, Tuesday, July 3, 2012 |
A Seminar by Dr Chan Lo Kong 1:00 PM, Thursday, June 21, 2012 |
Jointly organized by Department of Pathology A Seminar Deciphering Tumor Genomes via Bioinformatics Approaches by Dr Derek CHIANG 5:00 PM, Friday, June 15, 2012 All are welcome MLT CPD code: 04121021 |
A Seminar p53 Regulators FBI-1 and iASPP in Ovarian Cancer by Professor Annie NY Cheung |
Department of Pathology presents Croucher Advanced Study Institute 2012 Introduction Cancer is the major cause of death in Hong Kong as in most parts of the world. Traditional studies on cancer emphasize on the roles of genetic and epigenetic changes in cancer cells. In recent years, increasing volume of literature identifies the important interaction between tumour cells and the surrounding stroma. Such tumour microenvironment comprises of complicated networking including cellular and non-cellular components and affects crucial signaling pathways factors that control tumour invasion and metastasis, chemoresistance and response to metabolic stress. Understanding of the most advanced breakthroughs and development in this field is of great importance to cancer researchers. It is expected that such knowledge is of utmost importance in developing novel prognostic marker that can better predict outcome of cancer patients as well as innovative therapeutic targets that can overcome chemoresistance and improve survival of our cancer patients. These concepts are included as main themes of the proposed ASI. The lecturers are all well-renowned masters of the field and have contributed to high impact research. It will provide a precious opportunity for researchers from Hong Kong and the region to be enlightened directly and interactively from the masters in the field. The ASI also makes available a valuable platform of scientific networking which facilitates collaborative interactions among the local participants and the masters. Opening Address by Professor Paul K.H. TAM Professor S.P. Lee Professor Annie N.Y. CHEUNG Open Lectures by
Director Annie Nga-Yin CHEUNG Organizing Committee
For registration and enquiry, please contact Miss Jackie Luk Croucher Foundation The Croucher Foundation is an independent private foundation established by the late Noel Croucher in 1979 to promote the standard of the natural sciences, technology and medicine in Hong Kong
Croucher Advanced Study Institute An Advanced Study Institute (ASI) is a high-level teaching activity where a carefully defined subject, systematically presented, is treated in depth by lecturers of international standing, and new advances in a subject, not taught elsewhere, are reported in tutorial form. ASIs, as short courses, contribute to the dissemination of knowledge and the formation of international scientific contacts. The teaching in ASIs is aimed at established scientists with substantial scientific background in the topic being proposed.
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The role of metabonomics in exploring disease etiology by Yulan Wang December 12, 2011 All are welcome |
Department of Pathology and The Centre for Cancer Research A Seminar Manipulating Lgr5 stem cells of the intestine by Professor Hans Clevers November 14, 2011 4:30PM to 6:00PM All are welcome |
State Key Laboratory for Liver Research and Department of Biochemistry, HKU Induction of functional hepatocyte-like cells from mouse fibroblasts by Dr HUI Lijian All are welcome MLT CPD code: 04111101 |
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Advances in Mass Spectrometry Symposium 2011 Co-organized by the Department of Pathology,
All are welcome |
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MicroRNA in the Molecular Genetic Alterations by Professor Irene Oi Lin Ng 1:00 PM, Thursday, July 28, 2011 All are welcome |
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Direct Regulation of Cancer Stem Cell Marker CD133 by c-Myc is Modulated by Dr Kan Junsuo |
RESEARCH POSTGRADUATE STUDENTS (RPGS) RETREAT Date: 15th July, 2011 *********** 1:10PM CHAN Wing Lim Wallace - 2nd Yr MPhil student of Dr. John Nicholls 1:35PM SO King Yan, Leo - 2nd Yr MPhil student of Dr. John Nicholls 2:00PM LUI Wing Chi Winnie - 2nd Yr PhD student of Dr. Ray Ng 2:25PM MA Wei - 2nd Yr PhD student of Professor Irene Ng 2:50PM TSUI Yu Man - 2nd Yr PhD student of Professor Irene Ng 3:15PM Tea Break 3:30PM FAN Ngo Yin Dorothy – 2nd Yr PhD student of Dr. Jack Wong 3:55PM AU Leung Kuen, Sandy – 4th Yr PhD student of Dr. Jack Wong 4:20PM MAK Chun Yin Victor - 3rd Yr PhD student of Professor Annie Cheung 4:45PM LAU Lai Yee - 3rd Yr PhD student of Professor US Khoo 5:10PM CHEN Jie - 4thYr PhD student of Professor US Khoo 5:35PM Prize giving & closing remarks by Adjudicator:
For any further enquiries, please email Ms Irene Tong |
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Introduction to Roche cobas genomics & oncology portfolio by Mr Brian Earp 1:00 - 2:00 PM, Tuesday, July 12, 2011 All are welcome |
A Seminar Colorectal Cancer: From Genetics to Epigenetics by Dr Chan Tsun Leung, Chris |
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Molecular Dissection and Targeting of Leukemic Stem Cells by Professor So Chi Wai, Eric |
A Seminar Update on Thalassemia Research in Thailand by Professor Suthat FUCHAROEN 11:30 AM, Thursday, May 26, 2011 |
A Seminar Phosphorylation of DLC1 Tumor Suppressor: by Dr Yam Wai Ping, Judy 1:00 PM, Thursday, May 19, 2011 |
A Seminar Dr Wong Pik, Maria 1:00 PM, Thursday, May 12, 2011 |
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Diagnosing Beta Thalassaemia Trait in by Dr So Chi Chiu, Jason MLT CPD code: 04101451 |
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Demystifying Medical Humanities - by Professor Chan Li Chong |
Jointly organized by & Department of Pathology A Seminar Epigenetic Regulation of Hepatic Stellate Cells: |
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Biomarker & Target of Liver Cancer by Professor Wang Hong-Yang 1:00 PM, Friday, April 8, 2011 |
Jointly organized by A Seminar WASP, WIP and Podosome Dynamics by 5:00 PM, Wednesday, March 23, 2011 All are welcome |
Jointly organized by A Seminar PAK4 and Cancer Cell Migration by Dr Claire Wells 1:00 PM, Wednesday, March 23, 2011 |
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Roles of B Cells in Autoimmunity
by Dr Liwei Lu |
A Seminar Cancer Stem Cells Switch Between Two Distinct Phenotypes by |
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Killing Them, Killing Us |
RESEARCH POSTGRADUATE STUDENTS (RPGS) RETREAT 2:10PM Yuen Kit Man - 2nd Yr MPhil student of Dr. John Nicholls 2:35PM Cheung Chi Ho Vincent - 2nd Yr MPhil student of Dr. Terence Lee 3:00PM Ho Siu Ki Eric - 2nd Yr MPhil student of Dr William Choi 3:25PM Wong Kit Man Sunny – 2nd Yr MPhil student of Dr. Maria Wong 3:50PM Tea Break 4:10PM Wong Yuen Sze Sivia – 2nd Yr MPhil student of Dr. Judy Yam 4:35PM MAK Chun Yin Victor - 3rd Yr PhD student of Professor Annie Cheung 5:00PM Inspirational talk for current RPGs by Dr Ray Ng, Research Assistant Professor 5:10PM Prize giving & closing remarks by Adjudicator Dr. Eric Tse (Clinical Associate Professor, Department of Medicine, HKU) For any further enquiries, please contact Ms Irene Tong at 2255 3967 |
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Phosphatase and Tensin Homolog (PTEN) Dr Sze Man Fong, Karen |
Joint Seminar Understanding Protein Professor John R. YATES III 5:00 PM, January 25, 2011 (Tuesday)
Pathology All are welcome |
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Retinoic Acid Receptor Responder 3 Expression by Dr Yan Hoi Ning, Helen |
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Gene Expression Programme of by Professor Leung Suet Yi |
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by Dr Ko Chi Fat, Frankie |
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Does Hepatitis B x Antigen Promote the Appearance by Mark Feitelson, Ph.D. 12:00 PM, Monday, December 20, 2010 All are welcome MLT CPD code: 04101311 |
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Controlling Seasonal and Pandemic Influenza: by Dr Chan Wan Yi, Renee |
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Study of Translation Initiation Efficiency Differentially by Dr Cheung Yuen Nei 1:00 PM, Thursday, November 25, 2010 |
A Seminar The Akt-FOXO3a Signaling Axis in Breast Cancer by Professor Khoo Ui Soon Department of Pathology The University of Hong Kong 1:00 PM, Thursday, November 18, 2010 Lecture Theatre University Pathology Building Queen Mary Hospital All are welcome MLT CPD code: 04101261 |
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Epigenetic Regulation of AKAP12 in Human Hepatocarcinogenesis by Dr Odilia Popanda 1:00 PM, Tuesday, November 16, 2010 |
Jointly organized by A Historical Lecture on Stem Cell Regeneration and the Myth of Prometheus by Professor John Rasko |
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Alterations in Wnt Signaling Pathway in Hepatocellular Carcinoma by Dr Tung Kwok Kwan, Edmund |
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Genetic Abnormalities of NF-kB Regulators in DLBCL by Dr Chen Yun Wen, Wendy |
13th - 15th October 2010 Jointly Organised by and KATHARINE DORMANDY HAEMOPHILIA CENTRE |
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Making and Breaking the Link - by Dr John Nicholls 1:00 PM, Thursday, September 30, 2010 |
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Epigenetic Modifying Enzymes in by Professor So Chi Wai, Eric 5:00 PM, Monday, September 13, 2010 |
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Development of Stem Cell & Regenerative Medicine in HK: by Professor Ronald Li |
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The Hong Kong College of Pathologists and Department of Pathology A Seminar Histopathology External Quality Assurance (EQA) Schemes and by Dr Raymond McMahon 5:00 - 6:00 PM All are welcome HKCPath - 1 CME point |
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Identifying Hepatocellular Carcinoma Susceptible Loci by Dr Chan Yuen Kwong, Kelvin |
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MicroRNA-616 Induces Androgen-independent Growth of Prostate Cancer Cells by Dr Ma Kwai Yee, Stephanie 1:00 PM, Thursday, July 29, 2010 |
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RESEARCH POSTGRADUATE STUDENTS (RPGS) RETREAT Date: July 16, 2010 (Friday) Time: 2:00 – 5:30 pm Venue: Lecture Theatre, University Pathology Building, *********** PROGRAMME (20 min presentation + 5 min discussion) 2:00 pm - Opening remarks 2:35 pm - ‘Population differences in genomic alterations of sporadic basal cell carcinoma of the skin’ 3:00 pm - ‘Identification of microRNAs associated with tamoxifen resistance in breast cancer’ 3:25 pm - ‘Novel function of BAFF in the induction of IL-10-producing regulatory B cells’ 3:50 pm - Coffee/Tea break 4:35 pm - ‘Caveolin-1 promotes hepatocellular carcinoma tumourigenesis migration and invasion via MET-ERK1/2 pathway’ 5:00 pm - Inspirational talk for current RPGs by 5:15 pm - Prize giving & closing remarks by Adjudicators:- Professor Xin-Yuan Guan (Department of Clinical Oncology, HKU) For any further enquiries, please contact Ms Irene Tong All are welcome |
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& Centre for Reproduction, Development and Growth Presents A seminar Induced Pluripotent Stem Cell Therapy for Human Diseases, Are We There Yet? by Professor Yupo Ma 4:00 PM, Friday, June 25, 2010 All are welcome MLT CPD code: 04101141 |
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Using Clinical Outcomes Data to Improve Patient Care by Professor Laurie W Shroyer All are welcome |
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& Centre for Cancer Research Presents A seminar Molecular Diagnoses of Cervical Neoplasia: by Professor Kenneth R Shroyer All are welcome |
A Seminar Clinical Applications of Stem Cells in Cardiovascular Diseases by |
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The Art of Science and the Science of Art by Dr Lam Lai Kwan, Queenie |
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Identification of Liver Cancer Stem Cells Using by Dr Lee Kin Wah, Terence 1:00 PM, Thursday, May 20, 2010 |
The Department of Pathology You are cordially invited to attend our poster sharing session for research exchange and potential collaboration. Date: May 19, 2010 (Wednesday) Time: 5:00PM - 6:00PM Venue: 1/F, University Pathology Building, Queen Mary Hospital Light refreshment will be served All are welcome ******************** Posters to be presented: 1. CD24 is a functional marker that mediates liver tumor initiation via regulation of Nanog 2. Dysregulated expression of stem cell transcription factor Nanog in development and progress of ovarian cancers 3. Deleted in Liver Cancer 1 (DLC1) is a negative regulator of metastasis and deregulated by kinase phosphorylation in hepatocellular carcinoma 4. Dysregulated expression and function of Plexin-B1 in ovarian cancers 5. Examination of eIF4E level in human breast cancer and study the role of eIF4 in regulating translation of various splice variants of breast cancer genes 6. iASPP and Chemoresistance in ovarian Cancers - Effects on Paclitaxel-mediated mitotic catastrophe 7. Isolation, expansion and characterization of CD44 positive cells as tumor-initiating/stem/progenitor cells in non-small cell lung cancer 8. microRNA-616 induces androgen-independent growth of prostate cancer cells through suppression of TFPI-2 expression 9. Molecular features and functional consequence of CD44 activation by a novel recurrent IGH translocation t(11;14) (p13;q32) in mature B- cell lymphoid neoplasm 10. Nuclear targeted Deleted in Liver Cancer 1 exhibited reduced tumor suppressive function both in vitro and in vivo 11. Nucleophosmin (Theronine 234) is a novel mediator of tumor metastasis 12. Retinoic acid receptor responder 3 expression suppresses colorectal cancer cell growth in vitro and is a stage-independent prognostic marker in colorectal cancer patients in vivo 13. The Role of CpG Island Methylator Phenotype 2 (CIMP2) in Early Onset Colorectal Cancer Patients 14. Serum level of DKK1 as a marker for predicting tumor recurrence of hepatocellular carcinoma |
A Seminar by Dr Wong Chun Ming, Jack |
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by Dr Leung Lai Han, Elaine |
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Molecular Classification of Diffuse Large B-cell Lymphoma by Dr Choi Wai Lap, William |
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Reversible Epigenetic Silencing of CD44 During B Cell Development by Professor Gopesh Srivastava 1:00 PM, Thursday, March 4, 2010 |
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by Dr Siu Kwan Yee, Michelle |
Department of Pathology |
Department of Pathology A Seminar Melamine and Beyond by Professor Lam Ching Wan 1:00 PM, Thursday, January 28, 2010 All are welcome MLT CPD code: 04101021 |
A Seminar Dysregulated Expression and Function of Plexin-B1 in Cancers by Dr Wong Gee Wan, Oscar Post-doctoral Fellow Department of Pathology The University of Hong Kong 1:00 PM, Thursday, December 17, 2009 G004, Conference Room University Pathology Building Queen Mary Hospital All are welcome MLT CPD code: 04091231 |
A Seminar by Professor POON Man Chiu |
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ROCK and Rho and Molecular Pathology of Liver Cancer
by
Professor Irene Ng
1:00 PM, Thursday, November 12, 2009 All are welcome
MLT CPD code: 04091201 |
A seminar jointly organized by The Hong Kong College of Pathologists Molecular Pathology of Colorectal Neoplasia by Dr Raymond McMahon 5:30 – 6:30 PM, Monday, September 28, 2009 All are welcome HKCPath - 1 CME point |
A Seminar Molecular Markers for by Professor Annie Cheung 1:00 PM, Thursday, August 6, 2009 All are welcome MLT CPD code: 04091171 |
A Seminar Jointly organized by |
A Seminar EGFR Mutations and Targets of Therapy |
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Update of the BRCA Genes in Breast by Dr Khoo Ui Soon 1:00 PM, Thursday, June 18, 2009 All are welcome |
A Seminar Of Viruses and Cells: by Dr Roberto Bruzzone 1:00 PM, Thursday, June 4, 2009 All are welcome MLT CPD code: 04091111 |
Department of Pathology jointly present A Seminar “Somatic mutations in human cancer: by Dr. P. Andrew Futreal 1:00 PM, Friday, May 22, 2009 All are welcome Biosketch: Dr. Futreal received his PhD in Pathology from the University of North Carolina in 1993. He then was an Assistant Professor at Duke University in the Departments of Surgery, Gynecologic Oncology and Genetics before moving to the to the UK in 2000 to start the Cancer Genome Project with Mike Stratton and Richard Wooster. He is currently Co-Director of the Cancer Genome Project with Mike Stratton and a Senior Investigator at the Wellcome Trust Sanger Institute. His research background includes work on identification of BRCA1 and BRCA2 as well as investigations into the somatic genetics of breast and gynaecological malignancies. His current research areas are using genome-based approaches to investigate the somatic genetics of human cancer - including high-throughput sequencing and array-based methods. This work has lead to the identification of BRAF as a new human cancer gene, and other progress including identification of ERBB2 mutations in lung cancer, FBXW7 and PTEN mutations in T-cell leukaemia, identification of chemo-resistance mechanisms in glioblastoma and identifying mutations implicating the histone modification machinery in solid tumours. His work also focuses on investigating the translation of basic research findings with a focus on applying somatic cancer genetics to clinical oncology problems. MLT CPD code: 04091121 |
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Study of Foetal Haemoglobin in Chinese by Dr So Chi Chiu, Jason 1:00 PM, Thursday, May 21, 2009 All are welcome MLT CPD code: 04091101 |
A Seminar Control of Fetal Haemoglobin Expression – by Professor Swee Lay THEIN 1:00 PM, Friday, May 8, 2009 All are welcome MLT CPD code: 04091071 |
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Autoimmune Arthritis and Its Experimental Therapy by Gene Silencing by Dr Liwei Lu 1:00 PM, Thursday, May 7, 2009 All are welcome MLT CPD code: 04091091 |
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Pernicious Anemia: by Professor Ban-Hock TOH 1:00 PM, Monday, May 4, 2009 All are welcome MLT CPD code:04091081 |
A Seminar Subcellular Localization of DLC1 by Dr Yam Wai Ping, Judy 1:00 PM, Thursday, April 9, 2009 All are welcome MLT CPD code: 04091061 |
A Seminar on Automated Image Analysis Introduction to Automated Image Analysis in Histological Sections - GenieTM Histology Pattern Recognition System - Microvessel Density Analysis by Mr Scott Spear Monday, April 6th, 2009 All are welcome |
A Seminar Wnt Signalling Pathway and Colorectal Cancer by Dr Yan Hoi Ning, Helen |
Official launch of the
University Pathology Laboratory on Thursday, March 12, 2009 6:00pm – 6:15pm 6:15pm – 6:45pm 6:45pm – 7:30pm All are welcome Brochure available here For further information, |
A Seminar The Application of Next Generation by Professor Si LOK |
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Jointly organised by New Core Imaging Facilities and their Applications - live cell imaging using the spinning disc confocal microscope - microscopic slide scanning and web-based virtual microscopy - tissue microarray and automated image analysis Speakers: Dr US Khoo Professor SY Leung 4:30PM – 5:45PM, Friday, 6 March 2009 All are welcome |
A Seminar
Prostate Cancer with a Twist, and a bit more by Dr Chan Kwok Wah |
A Seminar
What do we know about Homicides in Hong Kong? by Dr Philip Beh 1:00 PM, Thursday, February 19, 2009 All are welcome MLT CPD code:04091021 |
A Seminar
Mitotic checkpoint signaling in cancers – by Dr Sze Man Fong, Karen 1:00 PM, Thursday, January 22, 2009 All are welcome MLT CPD code:04091011 |
A Seminar
Influenza Receptors and by Dr John Nicholls 1:00 PM, Tuesday, December 30, 2008 All are welcome MLT CPD code:04081251 |
A Seminar
by Dr Hao Yuan KUEH 1:00 PM, Tuesday, December 16, 2008 |
A Seminar
Epimutations, mismatch repair and colorectal cancer by Professor Robyn Ward 1:00 PM, Tuesday, December 9, 2008 |
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by Dr Chan Tsun Leung, Chris |
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Proteasome inhibitor bortezomib-induced by Dr Shen Lijun 1:00 PM, Thursday, November 27, 2008 All are welcome MLT CPD code:04081201 |
A Seminar
The molecular basis of hereditary diffuse gastric cancer by Dr Parry Guilford All are welcome |
A Seminar
CD133: A Window into Cancer Stem Cells in the Liver by Dr Ma Kwai Yee, Stephanie Post-doctoral Fellow Department of Pathology The University of Hong Kong 1:00 PM, Tuesday, November 11, 2008 G004, Conference Room University Pathology Building Queen Mary Hospital All are welcome MLT CPD code: 04081191 |
Croucher Advanced Study Institute presents Molecular Genetics and Cell Signaling in Cancer and Cancer Metastasis November 05, 2008 (Wednesday) For full program details, please click here |
COAGULATION WORKSHOP
29th - 31st October 2008 Jointly Organised DEPARTMENT OF PATHOLOGY and KATHARINE DORMANDY HAEMOPHILIA CENTRE |
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Modulators of reactive oxygen species generation by Dr Yeung Ho Yee, Bonnie 1:00 PM, Thursday, October 23, 2008 All are welcome MLT CPD code:0408181 |
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Colorectal cancer - gene expression profiling, genetics, epigenetics, by Professor SY Leung 1:00 PM, Thursday, October 16, 2008 All are welcome MLT CPD code:0408171 |
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EGFR and Src - potential drug targets by Dr Leung Lai Han, Elaine 1:00 PM, Thursday, September 25, 2008 All are welcome MLT CPD code:0408161 |
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A Seminar
p53 and Akt - Molecular Signatures and Crosstalk in the Control of Chemosensitivity in Ovarian Cancer by Professor Benjamin K. Tsang 2:30 PM, Tuesday, September 2, 2008 |
| A Seminar Bone Marrow-derived Mesenchymal Stem Cells by Professor Yaojiong Wu |
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Gastric Lymphoma: by |
A Seminar
Carboxypeptidase E: a surprising link between by Dr Lee Kin Wah, Terence |
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Granulin-epithelin Precursor: a potential cancer therapeutic target by Dr Ip Ying Chi, Jovian 1:00 PM, Thursday, June 26, 2008 All are welcome MLT CPD code:04081091 |
A Seminar The Role of Phytocompounds in by Professor Sandra Miller 4:00 PM, Tuesday, April 29, 2008 All are welcome MLT CPD code:04081061 |
A Seminar
Contribution of Genetic Variants to Disease Risk by Dr Kelvin YK Chan 1:00 PM, Thursday, April 24, 2008 All are welcome MLT CPD code:04081051 |
DEPARTMENT OF PATHOLOGY Presents The Inaugural Hou Pao-Chang Distinguished Lecture
All are welcome For further information, please feel free to contact Abstract Multicellular organisms devote many different, genetically-defined pathways to their responses to injury. Some of these are shared by unicellular organisms (e.g. the heat shock, unfolded protein and autophagy responses). Others (including apoptosis) are widely employed by multicellular organisms, in which they also participate in the shaping of tissues and organs in normal development. Deficiency in these pathways carries high biological costs that include cancer, disorders of immunoregulation, and degenerative diseases of the CNS. This lecture focuses on the activation of apoptosis in cells that have been exposed to ionising radiation, a circumstance in which they receive double-strand DNA breaks. It discusses how injury signals are coupled to the apoptosis effector mechanism, how the threshold for activating cell death may be modified, and how, following injury, the death sentence may be repealed by the intra-nuclear particles called PML bodies. Finally, it seeks to indicate the relevance of these cellular reactions to human carcinogenesis. About the speaker Professor Andrew Wyllie graduated from Aberdeen University in Medicine in 1967 and completed his PhD there in 1975 under the supervision of Sir Alastair Currie. It was at this time, with Professor John Kerr from the University of Queensland, that his interest in the processes of cell death began. In 1972 he was co-author of the first paper formally describing the process of apoptosis and much of his research since then has been occupied with the cell and molecular biology of this process and its relevance in cancer. A histopathologist by training, he has worked in the Royal Postgraduate Medical School of London and the University of Edinburgh (where he was Head of Department until 1998), before taking up his present post as Professor of Pathology in the University of Cambridge. His current main research interest is the role of apoptosis in the genesis and treatment of human cancer, and colorectal cancer in particular. Apoptosis is now the focus of intense research in many laboratories worldwide and is the subject of thousands of articles. Wyllie’s contribution has been recognised in international awards including the Bertner Award of the M D Anderson Cancer Center, the Canadian Gairdner Foundation International Award and the Scheele Prize of the Swedish Pharmaceutical Society. He is a Fellow of the Royal Society and the Royal Society of Edinburgh, and a member of the Academia Europea and the British Academy of Medical Sciences. Throughout his career, and at present, he has been involved in teaching medical and other undergraduates the basic processes that underlie disease. He is married, with three children. MLT CPD code:04081041 |
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Molecular Pathology and Clinical Behaviour of Colorectal Cancer by Professor Andrew H Wyllie 12:00 Noon, Wednesday, April 9, 2008 All are welcome MLT CPD code: 04081041 |
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Interferon: a Fight for Supremacy in SARS by Dr Eleanor N Fish, PhD 12:00 Noon, Tuesday, March 25, 2008 All are welcome MLT CPD code:04081021 |
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Guiding the 'Misguided Immunity' - Functional Conditioning of Dendritic Cells by Dr Fang-Ping Huang 1:00 PM, Friday, March 14, 2008 All are welcome MLT CPD code:04081011 |
A Croucher Foundation Conference Stem Cells in Leukemia and Lymphoma: Date: January 22-24, 2008 |
A Seminar
MALT Lymphoma: from Morphology to Molecule by Professor Ming-Qing Du Professor of Oncological Pathology Division of Molecular Histopathology Department of Pathology, University of Cambridge Addenbrooke's Hospital, Cambridge, United Kingdom 12:00 Noon, Tuesday, December 4, 2007 |
Modelling Breast Cancer in Yeast by Professor Bik Tye All are welcome |
A Seminar The MLL Recombinome by Dr Claus Meyer 1:00 PM, Thursday, October 4, 2007 All are welcome MLT CPD code: 07041111 |
A Seminar Epigenetic and pathomolecular mechanisms in t(4;11) leukemia by Professor Rolf Marschalek
1:00 PM, Thursday, September 27, 2007 |
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Molecular Pathology and Genetic Alterations in Hepatocellular Carcinoma by Professor Irene Ng MLT CPD code: 07041091 |
A Seminar Biomarkers in TGF-b Signaling Pathway as Predictors for Breast Cancer Risk and Survival by Professor Wei Zheng, M.D., Ph.D. Ingram Professor of Cancer Research Professor and Director Vanderbilt Epidemiology Center Vanderbilt University School of Medicine, USA 12:00 noon, Friday, June 29, 2007 Lecture Theatre University Pathology Building Queen Mary Hospital All are welcome MLT CPD code: 07041081 |
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A Seminar Human Papilloma Virus: by Professor Annie Cheung |
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Immuno-biology of Intestinal Dendritic Cells by Professor G Gordon MacPherson 1:00 PM, Tuesday, April 17, 2007 All are welcome MLT CPD code: 07041041 |
A Seminar Epidermal Growth Factor Receptor Mutations by Dr Maria Wong
MLT CPD code: 06041201 |
Differential Regulation of Autoimmune Responses by 1:00 PM, Thursday, November 9, 2006 |
A Seminar Differentiation and Memory Generation by Professor Changyou Wu 1:00 PM, Wednesday, October 25, 2006 All are welcome MLT CPD code: 06041181 |
A Seminar Novel Globin Variants – Diagnostic Problems by Dr Jason So 1:00 PM, Thursday, October 19, 2006 All are welcome MLT CPD code: 06041171 |
Seminar by Professor Xin Lu
Director of Research, Ludwig Institute for Cancer Research
University College London, United Kingdom
"ASPP, p53 Polymorphism and Cancer Susceptibility"
8 February 2007
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The Ninth James Gibson Lecture by Professor Xin Lu
Director of Research,
Ludwig Institute for Cancer Research
University College London,
United Kingdom
"P53: A Heavily Dictated “Dictator” of Life and Death"
7 February 2007
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The Croucher Foundation Advanced Study Institute on
“Molecular Genetics and Cell Signaling in Cancer and Cancer Metastasis”
Department of Pathology
The University of Hong Kong, Hong Kong
29 January - 2 February 2007
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Seminar by Professor Cecilia LW Chan
Professor, Department of Social Work and
Social Administration, and
Director, Centre on Behavioral Health
The University of Hong Kong
"Resilience and Growth: Chinese Medicine Perspective on Health and Mental Health"
18 January 2007
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Seminar by Dr Liwei Lu
Assistant Professor
Department of Pathology, The University of Hong Kong
"Regulation of Dendritic Cell Maturation and Function"
12 October 2006
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Seminar by Professor Steve CL Lin
Professor in Surgery, Chair, Paediatric Surgery
Department of Biosurgery and Surgical Technology
Division of SORA, Imperial College London, UK
"CD34 Cells in Infection and Tumour"
23 June, 2006
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Seminar by Professor Tak Mak
Professor, Department of Medical Biophysics &
Department of Immunology, University of Toronto,
Director, Division of Cellular and Molecular Biology
Toronto, Ontario, Canada
"Cell Death and DNA Repair"
12 June, 2006
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Seminar by Dr Han You
Postdoctoral Fellow, The Campbell Family Institute for Breast Cancer Research
University Health Network, Toronto, Canada
"Crosstalks between p53 and FOXO"
12 June, 2006
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Seminar by Professor Qingge LI
Professor and Deputy Dean, Molecular Diagnostics Laboratory, Department of Biomedical Sciences,
School of Life Sciences, Xiamen University, PR China
"Multiplex Real-time PCR-based Genotyping: Method and Applications"
4 May 2006
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Seminar by Professor Hans Clevers
Hubrecht Laboratory, Netherlands Institute for Developmental Biology
The Royal Netherlands Academy of Arts and Sciences, Utrecht,
The Netherlands
“Wnt and Notch cooperate to maintain proliferative compartments in crypts and intestinal neoplasia”
2 May 2006
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Croucher Advanced Study Institute on “Molecular Genetics & Cell Signaling in Cancers”
Department of Pathology
The University of Hong Kong, Hong Kong
24 April 2006
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Fourth Departmental Research Postgraduate Retreat
Department of Pathology
The University of Hong Kong, Hong Kong
22 April 2006
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Seminar by Professor Fung Chin Wan, Peter
Chair Professor, Department of Medicine, Honorary Professor in the Departments of Psychiatry
and Electrical and Electronic Engineering, the University of Hong Kong, Hong Kong
"Water Colours of PCW Fung, from West to East and East to West"
23 March 2006
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Seminar by Professor Amin A Nanji
Professor, Pathology and Laboratory Medicine,
Dalhousie University School of Medicine, Canada
"Cyclooxygenase and Liver Injury"
22 March 2006
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Seminar by Dr Andrew Wong
Former Instructor of
Department of Human Genetics,
Emory University, Atlanta, USA
"Array-based Comparative Genomic Hybridization (CGH)
and Its Application in Clinical Diagnostics"
17 March 2006
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Seminar by Professor Robin A Cooke
Mayne Medical School, University of Queensland, and Queensland Health Pathology Services;
Editor of International Pathology, the Official News Bulletin of the IAP
"Medical History and Teaching methods from the Renaissance" - January 11, 2006
"The changing face of pathology in a stone age people brought suddenly into contact with late 20th century culture"
12 January 2006
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Seminar by Dr Daniel Sze
Cancer Institute NSW Fellow & Head,
Cancer Immunology Group, Faculty of Pharmacy,
University of Sydney
"Update in Anti-myeloma T-cell and NK-cell Research"
4 January 2006
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Seminar by Professor Tak Mak
Professor, Department of Medical Biophysics
& Department of Immunology, University of Toronto,
Director, Division of Cellular and Molecular Biology
Toronto, Ontario, Canada
"Mapping Cell Survival Pathways in Cancer Cells"
3 January 2006
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2005 Departmental Christmas Party
21 December 2005
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Seminar by Professor Stephen B Baylin
Associate Director for Research
The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, USA
"Epigenetic Gene Silencing in Cancer – a Layering of Chromatin Events for Establishing Transcriptional Repression"
9 December 2005
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The Eighth James Gibson Lecture by Professor Stephen B Baylin
Associate Director for Research
The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, USA
"The Journey To Understanding That Epigenetics Is A Critical Player In The Initiation And Progression Of Human Cancer"
8 December 2005
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Seminar by Professor Kenjiro Matsuno
Professor and Chair, Department of Anatomy
Dokkyo University School of Medicine, Japan
"Trafficking and role of dendritic cells in the liver immunity and tolerance"
25 October 2005
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Seminar by Professor Richard J Epstein
Head, Laboratory of Computational Oncology, Department of Medicine
The University of Hong Kong, Hong Kong
"Why Cancer is Good for the Human Race"
15 September 2005
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Seminar by Professor WL Wendy Hsiao
Acting Coordinator of the Full-time Course Program
School of Chinese Medicine
Hong Kong Baptist University, Hong Kong
"Mechanistic Study of the Anti-cancer Activities of Total Saponins from
Gynostemma Pentaphyllum (jiao-gu-lan) in a Novel Cell System"
28 July 2005
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Third Departmental Research Postgraduate Retreat
Department of Pathology
The University of Hong Kong, Hong Kong
16 July 2005
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Seminar by Dr Chan Kwok Wah
Senior Clinical Lecturer, Department of Pathology
The University of Hong Kong, Hong Kong
"Pathology of Kidney Transplant"
30 June 2005
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Seminar by Dr Xiao-Feng Lawrence LE
Department of Experimental Therapeutics
Division of Cancer Medicine, University of Texas M. D. Anderson Cancer Center
Houston, Texas, USA
"HER2-targeted Antibody Therapy: Mechanisms of Action"
16 June 2005
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Seminar by Dr Khoo Ui-Soon
Clinical Associate professor, Department of Pathology
The University of Hong Kong, Hong Kong
"Genetic Susceptibility to SARS Co-V Infection"
9 June 2005
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Seminar by Dr Annie NY Cheung
Clinical Associate Professor,
Department of
Pathology
The University of Hong Kong, Hong Kong
"Advances in the Understanding of Gestational Trophoblastic Disease:
Tissue Dynamics and Molecular Genetics"
5 May 2005
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Seminar by Dr Eric CW So
Team Leader, Haemato-Oncology Section
The Institute of Cancer Research
London, UK
"Cancer Stem Cells and Transformation Mechanisms Associated with MLL Oncoproteins"
24 March 2005
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Seminar by Professor Mark Feitelson
Professor of Pathology, Anatomy and Cell Biology
Thomas Jefferson University
Philadelphia, PA, USA
"How HBxAg Contributes to Hepatocellular Carcinoma"
9 March 2005
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Second Departmental Research Postgraduate Retreat
Department of Pathology
The University of Hong Kong, Hong Kong
29 January 2005
Croucher Advanced Study Institute on “Molecular Genetics & Cell Signaling in Cancers”
Department of Pathology
The University of Hong Kong, Hong Kong
17 - 21 January 2005
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2004 Departmental Christmas Party
17 December 2004
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First Departmental Research Postgraduate Retreat
Department of Pathology
The University of Hong Kong, Hong Kong
28 August 2004
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Seminar by Professor Gordon MacPherson
Reader in Experimental Pathology
Sir William Dunn School of Pathology
University of Oxford
Oxford, UK
"Immunophysiology of Migrating Dendritic Cells"
25 May 2004
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Seminar by Professor Peter Vanezis
Chief Medical Officer and Head
Department of Forensic Medical Services
Forensic Science Service,
UK
"Next of Kin Clinics"
4 March 2004
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The Seventh James Gibson Lecture by Professor Neil D Theise
Beth Israel Medical Centre
New York, USA
"New Principles of Cell Plasticity"
2 December 2003
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Stem
Cell Symposium
Department of Pathology
The University of Hong Kong, Hong Kong
1 December 2003
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