Journal articles, book chapters and other published papers (2005 - 2006)

Publication in refereed journal

Au W.Y., Chan L.C., Liang R.H.S. and Kwong Y.L., Myelodysplastic syndrome and acute myeloid leukemia after treatment with fludarabine, mitoxantrone, and dexamethasone, American Journal of Hematology. 2006, 81(6): 471-3.

Chan A.Y., Luo H.Y., Wang W., Chui D.H., Ma E.S.K., Chan L.C. and Chong S.S., Diagnostic pitfall in PCR-based alpha-thalassemia genotyping resulting from a (G->C) polymorphism at nucleotide 71 3' to the alpha2-globin gene termination codon, Chinical Chemistry. 2006, 52(3): 536-7.

Chan V.S.F., Chan Y.K., Chen Y., Poon L.L.M., Cheung A.N.Y., Zheng B., Chan K.H., Mak W.W., Ngan H.Y.S., Xu X., Screaton G., Tam P.K.H., Austyn J.M., Chan L.C., Yip S.P., Peiris J.S.M., Khoo U.S. and Lin C.L., Homozygous L-SIGN (CLEC4M) plays a protective role in SARS coronavirus infection. , Nature Genetics. 2006, 38: 38-46.

Kong C.T., Sham M.H., So C.W.E., Cheah K.S.E., Chen S.J. and Chan L.C., The Mll-Een knockin fusion gene enhances proliferation of myeloid progenitors derived from mouse embryonic stem cells and causes myeloid leukaemia in chimeric mice, Leukemia. 2006, 20: 1829–1839.

Kwan T.F., Liang R.H.S., Verfaillie C.M., Ekker S.C., Chan L.C., Lin S. and Leung A.Y.H., Regulation of primitive hematopoiesis in zebrafish embryos by the death receptor gene, Experimental Hematology . 2006, 34(1): 27-34.

Li C.K., Chik K.W., Ha S.Y., Lee A.C., Yuen H.L., Ling S.C., Lee V., Chan G.C.F., Shing M.M., Chan L.C. and Ng M.H., Improved outcome of acute lymphoblastic leukaemia treated by delayed intensification in Hong Kong children: HKALL97 study, Hong Kong Medical Journal. 2006, 12(1): 33-9.

Wang W., Chan A.Y., Chan L.C., Ma E.S.K. and Chong S.S., Unusual rearrangement of the alpha-globin gene cluster containing both the -alpha3.7 and alphaalphaalphaanti-4.2 crossover junctions: clinical diagnostic implications and possible mechanisms, Clinical Chemistry. 2005, 51(11): 2167-70.

Wong J.G.W.S., Patil N.G., Beh S.L., Cheung E.P.T., Wong V., Chan L.C. and Mak-Lieh F., Cultivating psychological well-being in Hong Kong's future doctors, Medical Teacher. 2005, 27(8): 715-9.

Yip S.F., So J.C.C., Chan A.Y.Y., Liu H.S.Y., Wan T.S.K. and Chan L.C., The lack of association between JAK2 V617F mutation and myelodysplastic syndrome with or without myelofibrosis , Leukemia. 2006, 20(6): 1165.

Yip S.F., Wan T.S.K., Chan L.C. and Chan G.C.F., Trisomy 4 as sole karyotypic abnormality in acute lymphoblastic leukemia: Different clinical features and treatment response between B and T phenotypes?, Cancer Genetics and Cytogenetics. 2006, 164: 94-95.

Ajonuma L.C., Ng E.H.Y., Chan L.N., Chow P.H., Kung L.S., Cheung A.N.Y., Ho L.S., Briton-Jones C., Lok I.H., Haines C.J. and Chan H.C., Ultrastructural characterization of whole hydrosalpinx from infertile Chinese women, Cell Biology International. 2005, 29: 849-856.

Chan V.S.F., Chan Y.K., Chen Y., Poon L.L.M., Cheung A.N.Y., Zheng B., Chan K.H., Mak W.W., Ngan H.Y.S., Xu X., Screaton G., Tam P.K.H., Austyn J.M., Chan L.C., Yip S.P., Peiris J.S.M., Khoo U.S. and Lin C.L., Homozygous L-SIGN (CLEC4M) plays a protective role in SARS coronavirus infection. , Nature Genetics. 2006, 38: 38-46.

Cheung W.T., Au S.C., Cheung A.N.Y., Ngan H.Y.S., Tombran-Tink J., Auersperg N. and Wong A.S.T., Pigment epithelium-derived factor is estrogen sensitive and inhibits the growth of human ovarian cancer and ovarian surface epithelial cells, Endocrinology. 2006, 147(9): 4179-91.

Chiu P.M., Feng H., Benbrook D.M., Ngan H.Y.S., Khoo U.S., Xue W., Tsao G.S.W., Chan K.W. and Cheung A.N.Y., Effect of all-trans retinoic acid on tissue dynamics of choriocarcinoma cell lines: an organotypic model , Journal of Clinical Pathology . 2006, 59(8): 845-50.

Feng H., Tsao G.S.W., Ngan H.Y.S., Kwan H.S., Shih S.M., Xue W., Chiu P.M., Chan K.W. and Cheung A.N.Y., Differential gene expression identified in complete hydatidiform mole by combining suppression subtractive hybridization and cDNA microarray, Placenta. 2006, 27: 521-526.

Feng H., Tsao G.S.W., Ngan H.Y.S., Xue W., Chiu P.M. and Cheung A.N.Y., Differential expression of insulin-like growth factor binding protein 1 and ferritin light polypeptide in gestational trophoblastic neoplasia: combined cDNA suppression subtractive hybridization and microarray study, Cancer. 2005, 104(11): 2409-2416.

Fong P.Y., Xue W., Ngan H.Y.S., Chiu P.M., Chan Y.K., Tsao G.S.W. and Cheung A.N.Y., Caspase activity is downregulated in choriocarcinoma: a cDNA array differential expression study, Journal of Clinical Pathology. 2006, 59: 179-183.

Huang F.Y., Chiu P.M., Tam K.F., Kwok K.Y., Lau E.T., Tang M.H., Ng T.Y., Liu V.W.S., Cheung A.N.Y. and Ngan H.Y.S., Semi-quantitative fluorescent PCR analysis identifies PRKAA1 on chromosome 5 as a potential candidate cancer gene of cervical cancer, Gynecologic Oncology. 2006, 103(1): 219-25.

Li H.W., Leung S.W., Cheung A.N.Y., Yu M.M., Chan L.K. and Wong Y.F., Expression of maspin in gestational trophoblastic disease, Gynecologic Oncology . 2005, 101(1): 76-81.

Wang Y., Liu V.W.S., Xue W., Tsang P.C.K., Cheung A.N.Y. and Ngan H.Y.S., The Increase Of Mitochondrial Dna Content In Endometrial Adenocarcinoma Cells: A Quantitative Study Using Laser-captured Microdissected Tissues, Gynecologic Oncology. 2005, 98: 104-110.

Wang Y., Liu V.W.S., Tsang P.C.K., Chiu P.M., Cheung A.N.Y., Khoo U.S., Nagley P. and Ngan H.Y.S., Microsatellite instability in mitochondrial genome of common female cancers, International Journal of Gynecological Cancer. 2006, Suppl 1: 259-266.

Xue W., Feng H., Chan Y.K., Chiu P.M., Ngan H.Y.S., Khoo U.S., Tsao G.S.W., Chan K.W. and Cheung A.N.Y., Id helix-loop-helix proteins are differentially expressed in gestational trophoblastic disease., Histopathology. 2005, 47(3): 303-9.

Aggarwal A., Guo D.L., Hoshida Y., Yuen S.T., Chu K.M., So S., Boussioutas A., Chen X., Bowtell D., Aburatani H., Leung S.Y. and Tan P., Topological and functional discovery in a gene coexpression meta-network of gastric cancer, Cancer Research. 2006, 66(1): 232-41.

Davies H., Hunter C., Smith R., Stephens P., Greenman C., Bignell G., Teague J., Butler A., Edkins S., Stevens C., Parker A., O'Meara S., Avis T., Barthorpe S., Brackenbury L., Buck G., Clements J., Cole J., Dicks E., Edwards K., Forbes S., Gorton M., Gray K., Halliday K., Harrison R., Hills K., Hinton J., Jones D., Kosmidou V., Laman R., Lugg R., Menzies A., Perry J., Petty R., Raine K., Shepherd R., Small A., Solomon H., Stephens Y., Tofts C., Varian J., Webb A., West S., Widaa S., Yates A., Brasseur F., Cooper C.S., Flanagan A.M., Green A., Knowles M., Leung S.Y., Looijenga L.H., Malkowicz B., Pierotti M.A., Teh B.T., Yuen S.T., Lakhani S.R., Easton D.F., Weber B.L., Goldstraw P., Nicholson A.G., Wooster R., Stratton M.R. and Futreal P.A., Somatic mutations of the protein kinase gene family in human lung cancer, Cancer Research. 2005, 65(17): 7591-5.

Fan Y.S., Yuen S.T. and Leung S.Y., Calcified fibrous nodules in the heart: a case report, Pathology. 2006, 38(3): 273-5.

Giacomini C.P., Leung S.Y., Chen X., Yuen S.T., Kim Y.H., Bair E. and Pollack J.R., A Gene Expression Signature of Genetic Instability in Colon Cancer, Cancer Research. 2005, 65(20): 9200-5.

Guo D.L., Zhang J., Yuen S.T., Tsui W.Y., Chan A.S.Y., Ho C., Ji J., Leung S.Y. and Chen X., Reduced expression of EphB2 that parallels invasion and metastasis in colorectal tumors, Carcinogenesis. 2005, 27(3): 454-464.

Iacopetta B., Russo A., Bazan V., Dardanoni G., Gebbia N., Soussi T., Kerr D., Elsaleh H., Soong R., Kandioler D., Janschek E., Kappel S., Lung M., Leung C.S., Ko J.M., Yuen S.T., Ho J.W.C., Leung S.Y., Crapez E., Duffour J., Ychou M., Leahy D.T., O'donoghue D.P., Agnese V., Cascio S., Di Fede G., Chieco-Bianchi L., Bertorelle R., Belluco C., Giaretti W., Castagnola P., Ricevuto E., Ficorella C., Bosari S., Arizzi C.D., Miyaki M., Onda M., Kampman E., Diergaarde B., Royds J., Lothe R.A., Diep C.B., Meling G.I., Ostrowski J., Trzeciak L., Guzinska-Ustymowicz K., Zalewski B., Capella G.M., Moreno V., Peinado M.A., Lonnroth C., Lundholm K., Sun X.F., Jansson A., Bouzourene H., Hsieh L.L., Tang R., Smith D.R., Allen-Mersh T.G., Khan Z.A., Shorthouse A.J., Silverman M.L., Kato S. and Ishioka C., Functional categories of TP53 mutation in colorectal cancer: results of an International Collaborative Study, Annals of Oncology. 2006, 17(5): 842-7.

Lau S.K.P., Woo P.C.Y., Li S.M.K., Huang Y., Tsoi H.W., Wong H.L.B., Wong S.S.Y., Leung S.Y., Chan K.H. and Yuen K.Y., Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats., Proceedings of the National Academy of Sciences of the Unite States of America. 2005, 102: 14040–14045.

Leung S.Y., Ho C., Tu I.P., Li R., So S., Chu K.M., Yuen S.T. and Chen X., Comprehensive analysis of 19Q12 amplicon in human gastric cancers, Modern Pathology. 2006, 19: 854-863.

Li M., Ng S.M., Wang J., Lai L., Leung S.Y., Franco M., Peng Y., He M.L., Kung H.F. and Lin M.C., EFA6A Enhances Glioma Cell Invasion through ADP Ribosylation Factor 6/Extracellular Signal-Regulated Kinase Signaling (Li M. and Ng S.M. are equal first authors)., Cancer Research. 2006, 66(3): 1583-1590.

Ma L., Chan K.W., Trendell-Smith N.J., Wu A.Y.Y., Tian L., Lam A.C., Lo C.K., Chik S.C.C., Ko K.H., To K.W., Kam C.S.K., Li X., Yang C., Leung S.Y., Ng M.H. and Huang F., Systemic autoimmune disease induced by dendritic cells that have captured necrotic but not apoptotic cells in susceptible mouse strains, In: Ma L, Chan KW, Trendell-Smith NJ, Wu A, Tian L, Lam AC, Chan AK, Lo CK, Chik S, Ko KH, To CK, Kam SK, Li XS, Yang CH, Leung SY, Ng MH, Stott DI, MacPherson GG, Huang FP, European Journal of Immunology (In This Issue highlight, Editorial Comments). 2005, 35(11): 3364-75.

Tang S.F., Chan K.H., Cheng V.C.C., Woo P.C.Y., Lau S.K.P., Lam C.C.K., Chan T.L., Wu A.K.L., Hung I.F.N., Leung S.Y. and Yuen K.Y., Comparative host gene transcription by microarray analysis early after infection of Huh7 cell line by SARS coronavirus and human coronavirus 229E., Journal of Virology. 2005, 79: 6180-6193.

Chan D.W. and Ng I.O.L., Knock-down of hepatitis B virus X protein reduces the tumorigenicity of hepatocellular carcinoma cells, Journal of Pathology. 2006, 208(3): 372-80.

Ha S.Y., Chik K.W., Ling S.C., Lee A.C.W., Luk C.W., Lam C.W.K., Ng I.O.L. and Chan G.C.F., A randomized controlled study evaluating the safety and efficacy of deferiprone treatment in thalassemia major patients from Hong Kong, Hemoglobin. 2006, 30(2): 263-274.

Lee K.W., Man K., Ho J.W.Y., Wang X., Poon R.T.P., Xu Y., Ng T.P., Chu A.C.Y., Sun K.W., Ng I.O.L., Sun H.C., Tang Z.Y., Xu R. and Fan S.T., FTY720: a promising agent for treatment of metastatic hepatocellular carcinoma, Clinical Cancer Research. 2005, 11(23): 8458-8466.

Luk J.M.C., Lam C.T., Siu A.F.M., Lam B.Y.H., Ng I.O.L., Hu M.Y., Che C.M. and Fan S.T., Proteomic profiling of hepatocellular carcinoma in Chinese cohort reveals heat-shock proteins (Hsp27, Hsp70, GRP78) up-regulation and their associated prognostic values, Proteomics . 2006, 6(3): 1049-1057.

Ng D.C.H., Chan S.F., Kok K.H., Yam J.W.P., Ching Y.P., Ng I.O.L. and Jin D., Mitochondrial targeting of growth suppressor protein DLC2 through the START domain, FEBS Letters . 2006, 580(1): 191-8.

Pawlik T.M., Delman K.A., Vauthey J.N., Nagorney D.M., Ng I.O.L., Ikai I., Yamaoka Y., Belghiti J., Lauwers G.Y., Poon R.T.P. and Abdalla E.K., Tumor size predicts vascular invasion and histologic grade: Implications for selection of surgical treatment for hepatocellular carcinoma, Liver Transplantation. 2005, 11(9): 1086-92.

Wong C.M., Yam J.W.P., Ching Y.P., Yau T.O., Leung T.H.Y., Jin D. and Ng I.O.L., Rho GTPase-Activating Protein Deleted in Liver Cancer Suppresses Cell Proliferation and Invasion in Hepatocellular Carcinoma, Cancer Research. 2005, 65: 8861-8868.

Yuan H., Yuen R.M.F., Wong D.K.H., Sum S.M., Sablon E., Ng I.O.L. and Lai C.L., Impact of Precore and Core Promoter Mutations on Hepatic Histology in Patients with Chronic Hepatitis B, Alimentary Pharmacology and Therapeutics. 2005, 22: 301-307.

Yuen R.M.F., Tanaka Y., Ng I.O.L., Mizokami M., Yuen J.C.H., Wong D.K.H., Yuan H., Sum S.M., Chan O.O. and Lai C.L., Hepatic necroinflammation and fibrosis in patients with genotypes Ba and C, core-promoter and precore mutations, Journal of Viral Hepatitis . 2005, 12(5): 513-8.

Chan K.W., Lee P.Y., Lam A.K.Y., Law S.Y.K., Wong J. and Srivastava G., Clinical relevance of Fas expression in oesophageal squamous cell carcinoma, Journal of Clinical Pathology . 2006, 59(1): 101-4.

Chen W.Y.W., Hu X., Liang A.C.T., Au W.Y., So J.C.C., Wong M.L.Y., Shen L., Tao Q., Chu K.M., Kwong Y.L., Liang R.H.S. and Srivastava G., High BCL6 expression predicts better prognosis, independent of BCL6 translocation status, translocation partner, or BCL6 deregulating mutations, in gastric lymphoma, Blood. 2006, 108(7): 2373-83.

Fatima S., Chui C.H., Tang W.K., Hui K.S., Au H.W., Li W.Y., Wong M.M., Cheung F., Tsao G.S.W., Lam K.Y., Beh S.L., Wong J., Law S.Y.K., Srivastava G., Ho K.P., Chan A.S. and Tang J.C.O., Transforming capacity of two novel genes JS-1 and JS-2 located in chromosome 5p and their overexpression in human esophageal squamous cell carcinoma, International Journal of Molecular Medicine. 2006, 17(1): 159-170.

Ko J.M.Y., Yau W.L., Chan P.L., Lung H.L., Yang L.C., Lo P.H.Y., Tang J.C.O., Srivastava G., Stanbridge E.J. and Lung M.L., Functional evidence of decreased tumorigenicity associated with monochromosome transfer of chromosome 14 in esophageal cancer and the mapping of tumor-suppressive regions to 14q32, Genes Chromosomes Cancer. 2005, 43(3): 284-293.

Lo P.H., Leung A.C., Kwok C.Y., Cheung W.S., Ko J.M., Yang L.C., Law S.Y.K., Wang L.D., Li J., Stanbridge E.J., Srivastava G., Tang J.C.O., Tsao G.S.W. and Lung M.L., Identification of a tumor suppressive critical region mapping to 3p14.2 in esophageal squamous cell carcinoma and studies of a candidate tumor suppressor gene, ADAMTS9, Oncogene. 2006.

Ren Y., Law S.Y.K., Huang X., Lee P.Y., Bacher M., Srivastava G. and Wong J., Macrophage migration inhibitory factor stimulates angiogenic factor expression and correlates with differentiation and lymph node status in patients with esophageal squamous cell carcinoma, Annals of Surgery. 2005, 242(1): 55-63.

Wong M.L.Y., Tao Q., Fu L., Wong K.Y., Qiu G.H., Law F.B.F., Tin P.C., Cheung W.L., Lee P.Y., Tang J.C.O., Tsao G.S.W., Lam A.K.Y., Law S.Y.K., Wong J. and Srivastava G., Aberrant promoter hypermethylation and silencing of the critical 3p21 tumour suppressor gene, RASSF1A, in Chinese oesophageal squamous cell carcinoma, International Journal of Oncology. 2006, 28(3): 767-73.

Ying J., Li H., Seng T.J., Langford C., Srivastava G., Tsao G.S.W., Putti T., Murray P., Chan A.T.C. and Tao Q., Functional epigenetics identifies a protocadherin PCDH10 as a candidate tumor suppressor for nasopharyngeal, esophageal and multiple other carcinomas with frequent methylation, Oncogene. 2006, 25(7): 1070-80.

Ying J., Srivastava G., Hsieh W.S., Gao Z., Murray P., Liao S.K., Ambinder R. and Tao Q., The stress-responsive gene GADD45G is a functional tumor suppressor, with its response to environmental stresses frequently disrupted epigenetically in multiple tumors, Clinical Cancer Research. 2005, 11(18): 6442-6449.

Zhang M., Ko K.H., Lam Q.L.K., Srivastava G., Zheng B., Lau Y.L. and Lu L., Expression and function of TNF family member B cell-activating factor in the development of autoimmune arthritis, International Immunology. 2005, 17(8): 1081-1092.

Yuen H.F., Chua C.W., Chan Y.P., Wong Y.C., Wang X., Chan K.W., The significance of TWIST and E-cadherin in the metastatic progression of Prostate Cancer, Histopathology 2007.

Yuen H.F., Chua C.W., Chan Y.P., Wong Y.C., Wang X. and Chan K.W., Id proteins expression in prostate cancer: high-level expression of Id-4 in primary prostate cancer is associated with development of metastases, Modern Pathology 2006, 19(7): 931-41.

Ma S.K.Y., Guan X.Y., Beh S.L., Wong K.Y., Chan Y.P., Yuen H.F., Vielkind J. and Chan K.W., The significance of LMO2 expression in the progression of prostate cancer, The Journal of Pathology 2007.

Chan K.W. , Lee P.Y., Lam A.K.Y., Law S.Y.K., Wong J. and Srivastava G., Clinical relevance of Fas expression in oesophageal squamous cell carcinoma, Journal of Clinical Pathology 2006, 59(1): 101-4.

Yuen H.F., Chan Y.P., Wong M.L.Y., Kwok W.K., Chan K.K., Lee P.Y., Srivastava G., Law S.Y.K., Wong Y.C., Wang X. and Chan K.W., Up-regulation of TWIST in Oesophageal Squamous Cell Carcinoma is associated with neoplastic transformation and distant metastasis, Journal of Clinical Pathology 2007.

Lui S.L., Chan K.W., Tsang R.C.W., Yung S.S.Y., Lai K.N. and Chan D.T.M., Effect of rapamycin on renal ischemia-reperfusion injury in mice, Transplant International 2006, 19: 834-839.

Tang S.C.W., Chan K.W., Tang C.S.O., Lam M.F., Leung C.Y., Tse K.C., Li C.S., Ho Y.W., Tong K.L., Lai K.N., Chan D.T.M. and Hong Kong Nephrology Study Group ., Conversion of ciclosporin A to tacrolimus in kidney transplant recipients with chronic allograft nephropathy, Nephrology Dialysis Transplantation 2006, 21(11): 3243-51.

Chan G.S.W., Chim S., Fan Y.S. and Chan K.W., Focal segmental glomerulosclerosis after membranous glomerulonephritis in remission: temporal diversity of glomerulopathy after bone marrow transplantation, Human Pathology 2006, 37(12): 1607-10.

Chan G.S.W., Tse K.C., Lam M.F. and Chan K.W., Thrombotic microangiopathy in an allograft kidney: a diagnostic challenge, Histopathology. 2006, 48(6): 775-6.

Chiu P.M., Feng H., Benbrook D.M., Ngan H.Y.S., Khoo U.S., Xue W., Tsao G.S.W., Chan K.W. and Cheung A.N.Y., Effect of all-trans retinoic acid on tissue dynamics of choriocarcinoma cell lines: an organotypic model , Journal of Clinical Pathology . 2006, 59(8): 845-50.

Sy A.N., Lam T.P. and Khoo U.S., Subcutaneous panniculitislike T-cell lymphoma appearing as a breast mass: a difficult and chanllenging case appearing at an unusual site, Journal Ultrasound Medicine. 2005, 24(10): 1453-1460.

Wang Y., Liu V.W.S., Tsang P.C.K., Chiu P.M., Cheung A.N.Y., Khoo U.S., Nagley P. and Ngan H.Y.S., Microsatellite instability in mitochondrial genome of common female cancers, International Journal of Gynecological Cancer. 2006, Suppl 1: 259-266.

Xue W., Feng H., Chan Y.K., Chiu P.M., Ngan H.Y.S., Khoo U.S., Tsao G.S.W., Chan K.W. and Cheung A.N.Y., Id helix-loop-helix proteins are differentially expressed in gestational trophoblastic disease., Histopathology. 2005, 47(3): 303-9.

Chan M.C.W., Cheung C.Y., Chui W.H., Tsao G.S.W., Nicholls J.M., Chan Y.O., Chan W.Y., Long H.T., Poon L.L.M., Guan Y. and Peiris J.S.M., Proinflammatory cytokine responses induced by influenza A (H5N1) viruses in primary human alveolar and bronchial epithelial cells, Respiratory Research. 2005, 6: 135.

Cheung H.W., Chun C.S., Wang Q., Deng W., Hu L., Guan X.Y., Nicholls J.M., Ling M.T., Wong Y.C., Tsao G.S.W., Jin D. and Wang X., Inactivation of human MAD2B in nasopharyngeal carcinoma cells leads to chemosensitization to DNA-damaging agents, Cancer Research. 2006, 66(8): 4357-4367.

Cheung H.W., Ching Y.P., Nicholls J.M., Ling M.T., Wong Y.C., Hui C.M., Cheung A., Tsao G.S.W., Wang Q., Yuen P.W., Lo K.W., Jin D. and Wang X., Epigenetic inactivation of CHFR in nasopharyngeal carcinoma through promoter methylation, Molecular Carcinogenesis. 2005, 43(4): 237-245.

Nicholls J.M. and Peiris J.S.M., Good ACE, bad ACE do battle in lung injury, SARS, Nature Medicine. 2005, 11: 821-822.

Nicholls J.M., Butany J., Poon L.L.M., Chan K.H., Beh S.L., Poutanen S., Peiris J.S.M. and Wong M.P., Time course and cellular localization of SARS-CoV nucleoprotein and RNA in lungs from fatal cases of SARS, Public Library of Science Medicine . 2006, 3(2): e27.

Uiprasertkul M., Puthavathana P., Sangsiriwut K., Pooruk P., Srisook K., Peiris J.S.M., Nicholls J.M., Chokephaibulkit K., Vanprapar N. and Auewarakul P., Influenza A H5N1 replication sites in humans, Emerging Infectious Diseases. 2005, 11(7): 1036-1041.

Wang Q., Tsao G.S.W., Ooka T., Nicholls J.M., Cheung H.W., Fu S., Wong Y.C. and Wang X., Anti-apoptotic role of BARF1 in gastric cancer cells, Cancer Letters. 2005, xx: 1-14.

Ho J.C.M., Wong M.P. and Lam W.K., Lymphoepithelioma-like carcinoma of the lung, Respirology. 2006, 11: 539-545.

Nicholls J.M., Butany J., Poon L.L.M., Chan K.H., Beh S.L., Poutanen S., Peiris J.S.M. and Wong M.P., Time course and cellular localization of SARS-CoV nucleoprotein and RNA in lungs from fatal cases of SARS, Public Library of Science Medicine . 2006, 3(2): e27.

Tam I.Y.S., Chung L.P., Suen W.S., Wang E., Wong M.C.M., Ho K.K., Lam W.K., Chiu S.W., Girard L., Minna J.D., Gazdar A.F. and Wong M.P., Distinct epidermal growth factor receptor and KRAS mutation patterns in non-small cell lung cancer patients with different tobacco exposure and clinicopathologic features, Clinical Cancer Research. 2006, 12(5): 1647-53.

Zhu H., Lam D.C., Han K.C., Tin P.C., Suen W.S., Wang E., Lam W.K., Cai W.W., Chung L.P. and Wong M.P., High resolution analysis of genomic aberrations by metaphase and array comparative genomic hybridization identifies candidate tumour genes in lung cancer cell lines, Cancer Letters. 2006.

Ma L., Chan K.W., Trendell-Smith N.J., Wu A.Y.Y., Tian L., Lam A.C., Lo C.K., Chik S.C.C., Ko K.H., To K.W., Kam C.S.K., Li X., Yang C., Leung S.Y., Ng M.H. and Huang F., Systemic autoimmune disease induced by dendritic cells that have captured necrotic but not apoptotic cells in susceptible mouse strains, In: Ma L, Chan KW, Trendell-Smith NJ, Wu A, Tian L, Lam AC, Chan AK, Lo CK, Chik S, Ko KH, To CK, Kam SK, Li XS, Yang CH, Leung SY, Ng MH, Stott DI, MacPherson GG, Huang FP, European Journal of Immunology (In This Issue highlight, Editorial Comments). 2005, 35(11): 3364-75.

Wong O.H., Huang F. and Chiang A.K.S., Differential responses of cord and adult blood-derived dendritic cells to dying cells, Immunology (Cover Story). 2005, 116: 13-20.

Qu X., Yang M.X., Kong B.H., Qi L., Lam Q.L.K., Yan S., Li P., Zhang M. and Lu L., Hypoxia inhibits the migratory capacity of human monocyte-derived dendritic cells, Immunology and Cell Biology. 2005, 83(6): 668-73.

Zhang M., Ko K.H., Lam Q.L.K., Srivastava G., Zheng B., Lau Y.L. and Lu L., Expression and function of TNF family member B cell-activating factor in the development of autoimmune arthritis, International Immunology. 2005, 17(8): 1081-1092.

Zheng Y., Cao K., Ng S.P., Chua D.T.T., Sham J.S.T., Kwong D.L.W., Ng M.H., Lu L. and Zheng B., Complementary activation of peripheral natural killer cell immunity in nasopharyngeal carcinoma, Cancer Science. 2006, 97(9): 912-9.

Cheung H.W., Ching Y.P., Nicholls J.M., Ling M.T., Wong Y.C., Hui C.M., Cheung A., Tsao G.S.W., Wang Q., Yuen P.W., Lo K.W., Jin D. and Wang X., Epigenetic inactivation of CHFR in nasopharyngeal carcinoma through promoter methylation, Molecular Carcinogenesis. 2005, 43(4): 237-245.

Fan X.M., Jiang X., Gu Q., Ching Y.P., He H., Xia H.H.X., Lin M.C., Chan O.O., Yuen R.M.F., Kung H.F. and Wong B.C.Y., Inhibition of Akt/PKB by a COX-2 Inhibitor Induces Apoptosis in Gastric Cancer Cells, Digestion. 2006, 73(2-3): 75-83.

Leung H.Y., Ching Y.P., Yam J.W.P., Wong C.M., Yau T.O., Jin D. and Ng I.O.L., Deleted in liver cancer 2 (DLC2) suppresses cell transformation by means of inhibition of RhoA activity, Proc Natl Acad Sci U S A. 2005, 102: 15207-15212.

Ng D.C.H., Chan S.F., Kok K.H., Yam J.W.P., Ching Y.P., Ng I.O.L. and Jin D., Mitochondrial targeting of growth suppressor protein DLC2 through the START domain, FEBS Letters . 2006, 580(1): 191-8.

Wong C.M., Yam J.W.P., Ching Y.P., Yau T.O., Leung T.H.Y., Jin D. and Ng I.O.L., Rho GTPase-Activating Protein Deleted in Liver Cancer Suppresses Cell Proliferation and Invasion in Hepatocellular Carcinoma, Cancer Research. 2005, 65: 8861-8868.

Leung H.Y., Ching Y.P., Yam J.W.P., Wong C.M., Yau T.O., Jin D. and Ng I.O.L., Deleted in liver cancer 2 (DLC2) suppresses cell transformation by means of inhibition of RhoA activity, Proc Natl Acad Sci U S A. 2005, 102: 15207-15212.

Ng D.C.H., Chan S.F., Kok K.H., Yam J.W.P., Ching Y.P., Ng I.O.L. and Jin D., Mitochondrial targeting of growth suppressor protein DLC2 through the START domain, FEBS Letters . 2006, 580(1): 191-8.

Wong C.M., Yam J.W.P., Ching Y.P., Yau T.O., Leung T.H.Y., Jin D. and Ng I.O.L., Rho GTPase-Activating Protein Deleted in Liver Cancer Suppresses Cell Proliferation and Invasion in Hepatocellular Carcinoma, Cancer Research. 2005, 65: 8861-8868.

Yam J.W.P., Chan K.W., Ngan E.S.W. and Hsiao W.L., Genomic structure, alternative splicing and tissue expression of rFrp/sFRP-4, the rat frizzled related protein gene., Gene. 2005, 357: 55-62.

Conference paper

Au W.Y., Lie A.K.W., Liang R.H.S., Yuen P.W., Shek T.W.H. and Kwong Y.L., Secondary non-hematologic malignancies after allogeneic stem cell transplantation : incidence and molecular monitoring, 10th Congress of the International Society of hematology, Asian Pacific Division, Nagoya, Japan. Nagoya, Japan, 2004, 110.

Chan L.C., Chan A.S.Y., Hui E.C., Ha S.Y. and Ma E.S.K., Hb H Disease: Time to Screen?, Genetics and Population Health. Inaugural Conference of the Australian Public Health Genetics Consortium. 2004.

Chay G.W., Ma E.S.K. and Cheung Y.F., Ethnic Differences in Coagulation Factor Abnormalities After the Fontan Procedure, Ruby Jubilee Scientific Meeting, HK, 24-26 Sepember 2004 (Abstract in Hong Kong Journal of Paediatrics (new series). Hong Kong, Medcom Limited, 2004, 9 (suppl): 39.

Chay G.W., Lui M.C. and Cheung Y.F., Ethnic Differences in Coagulation Factor Abnormalities after the Fontan Procedure, 5th Guangdong - Hong Kong Paediatric Exchange Meeting, HK, 24 July 2004 . 2004.

Chen J.F., Ma E.S.K., Ha S.Y., Chan G.C.F., Chan A.Y.Y., Chan L.C. and Lau Y.L., The Effect of Mild b-Thalassaemia Mutations on Clinical Manifestation of b-Thalassaemia Major and Intermedia in Chinese, Ruby Jubilee Scientific Meeting, HK, 24-26 September 2004 (Abstract in Hong Kong Journal of Paediatrics (new series). Hong Kong, Medcom Limited, 2004, 9 (suppl): 18.

Chen J.F., Ma E.S.K., Ha S.Y., Chan G.C.F., Chan A.Y.Y., Chan L.C. and Lau Y.L., The Effect of Mild b-thalassaemia Mutations on Clinical Mainfestation of b-thalassaemia Major and Intermedia in Chinese, 5th Guangdong - Hong Kong Paediatric Exchange Meeting, HK, 24 July 2004 . 2004.

Cheung E.W.Y., Chay G.W., Ma E.S.K. and Cheung Y.F., Systemic Oxygen Saturation and Coagulation Factor Abnormalities Before and After the Fontan Procedure, 13th Annual Scientific Congress of Hong Kong College of Cardiology (abstract published in the Journal of the Hong Kong College of Cardiology), Hong Kong, 22-24 April 2005. 13: 53.

Chiang A.K.S., Wong O.H. and Huang F., Differential responses of cord and adult blood-derived dendritic cells to dying cells, The 3rd Congress of the Federation of Immunology Societies of Asia-Oceania, Hangzhou, PR China, 18-22 April 2005. C95.

Chiang A.K.S., Ma E.S.K., Jones B.M., Li Y.H., Chan G.C.F., Ha S.Y. and Lau Y.L., Long Term Immune Reconstitution after Bone Marrow Transplantation for Severe Combined Immunodeficiency and Wiskott Aldrich Syndrome, 《第五屆粵港兒科學術交流會，香港， 24 July 2004》, 2004, 47.

Chiang A.K.S., Ma E.S.K., Jones B.M., Li Y.H., Chan G.C.F., Ha S.Y. and Lau Y.L., Long Term Immune Reconstitution after Bone Marrow Transplantation for Severe Combined Immunodeficiency and Wiskott Aldrich Syndrome, 5th Guangdong - Hong Kong Paediatric Exchange Meeting, HK, 24 July 2004.

Chim S., Lee T.L. and Chan K.W., Propylthiouracil-induced ANCA Positive Crescentic Glomerulonephritis: A Case Report and Literature Review, Ruby Jubilee Scientific Meeting, HK, 24-26 Sepember 2004 (Abstract in Hong Kong Journal of Paediatrics (new series). Hong Kong, Medcom Limited, 2004, 9 (suppl): 46.

Chung B.H.Y., Ma E.S.K., Khong P.L. and Chan G.C.F., Genetic thrombophilic risk factors in Chinese children with malignant illness, The 3rd Hong Kong Medical Genetics Conference, HK< 8-10 April 2005. 23.

Gibson I., Cheung L.K., Chow S.P., Cheung W.L., Beh S.L., Savalani M.M. and Lee S.H., The use of rapid prototyping to assist medical applications, Processings of the 10th Assises Europoeennes du Prototypage Rapide. Paris, France, AFPR, 2004, CD-ROM: 1-8.

Ho J.C.M., Ho S.P., Chan M.M.W., Mak J.C.W., Ip M.S.M., Ko K.W., Yan C.P.K., Wong M.P., Tsang K.W.T. and Lam W.K., Non-small cell lung cancer in Chinese is associated with disturbance in systemic antioxidant profiles, 9th Congress of Asian Pacific Society of Respirology, Hong Kong, December, 2004. Respirology. 2004, 9 (Supp): A114.

Ho S.P., Chan M.M.W., Wong M.P., Tsang K.W.T., Ip M.S.M., Lam W.K. and Mak J.C.W., Transforming growth factor (TGF)-beta 1 gene common polymorphisms and plasma TGF-beta 1 levels in patients with lung cancer, 10th Medical Research Conference, Department of Medicine, The University of Hong Kong, February 2005. Abstract Book: RM 60.

Huang F., Induction of systemic autoimmune disease by dendritic cells that have captured dying cells, Proceedings of the 11th Asia Pacific League of Associations for Rheumatology Congress (APLAR 2004), International Convention Center, (ICC), Jeju, Korea, September 11-16, 2004.

Huang F., Ma L., Wu A.Y.Y., Tian L., Chan K.W., Trendell-Smith N.J., Lam A.C., Chan A.K.L., Lo C.K., Chik S.C.C., Ko K.H., To K.W., Kam S.K., Fong L.P., Li X.S., Leung S.Y., Ng M.H., Stott D.I., Liew F.Y. and MacPherson G.G., Systemic autoimmune disease induced by dendritic cells that have captured necrotic but not apoptotic dying cells, Proceedings of the 12th International Congress of Immunology and the 4th Annual Conference of FOCIS, Montreal, Canada, July 18-23, 2004.

Kok K.H., Choy E.Y.W., Ching Y.P. and Jin D., Cell-to-cell spreading of RNA interference in mammalian cells, The ASCB 44th Annual Meeting, Washington, DC, USA, 4-8 December 2004.

Lam B., Tam C.M., Lam S.Y., Wong M.P., Ooi C.G.C., Fung S.L., Ip M.S.M. and Lam W.K., Detection of early lung cancer in high risk population : a prospective study, 9th Congress of Asian Pacific Society of Respirology, Hong Kong, December 2004. Respirology. 2004, 9 (Supp): A122.

Law H.K.W., Cheung C.Y., Ng I.H.Y., Sia S.F., Chan Y.O., Luk W., Nicholls J.M., Peiris J.S.M. and Lau Y.L., Chemokine upregulation in SARS coronavirus infected human monocyte derived dendritic cells, Keystone Symposia: Dendritic cells at the Center of Innate and Adaptive Immunity: Eradication of Pathogens and Cancer and Control of Immunopathology, Vancouver, Canada, 1-7 February 2005. 85.

Law H.K.W., Cheung C.Y., Ng I.H.Y., Sia S.F., Luk W., Nicholls J.M., Peiris J.S.M. and Lau Y.L., Human Monocyte Derived Dendritic Cells Infected by SARS Associated Coronavirus, 12th International Congress of Immunology and 4th Annual Conference of FOCIS, Montreal, Canada, 18-23 July 2004.

Lee T.L., Kwok J.S.Y. and Lau Y.L., A Child with Behcet's Disease Associated with Natural Killer Cell Deficiency, Ruby Jubilee Scientific Meeting, HK, 24-26 Sepember 2004 (Abstract in Hong Kong Journal of Paediatrics (new series). Hong Kong, Medcom Limited, 2004, 9 (suppl): 48.

Liang Y., Zhang J.C.L., Higgins D.A. and Chan S.Y., Functional characteristics of SUN-2, 9th Research Postgraduate Symposium, HKU, 4 December 2004. 104.

Lo C.C., Wong K.Y. and Chan K.W., BRAF mutation in papillary thyroid carcinoma, 13th Annual Scientific Meeting of the Hong Kong Division of the International Academy of Pathology, Hong Kong, 12-14 November 2004.

Lo C.C., Wong K.Y. and Chan K.W., Ras mutation in papillary thyroid carcinoma, 13th Annual Scientific Meeting of the Hong Kong Division of the International Academy of Pathology, Hong Kong, 12-14 November 2004.

Ng D.C.H., Jin D. and Ng I.O.L., Characterisation of Steroidogenic Acute Regulatory Protein Related Lipid Transfer Domain (START)domain in Deleted in Liver Cancer 2(DLC-2). , Society For Chinese Bioscientists in America, Beijing, July 2004 . 2004.

Ng M.W., Law H.K.W., Yung R.W.H., Chow E.Y., Au K.L., Chan E.Y.T., Lim W., Peiris J.S.M. and Lau Y.L., Association of Monocyte Chemoattractant Protein 1 Gene Polymorphism with Severe Acute Respiratory Syndrome (SARS), Ruby Jubilee Scientific Meeting, HK, 24-26 Sepember 2004 (Abstract in Hong Kong Journal of Paediatrics (new series). Hong Kong, Medcom Limited, 2004, 9 (suppl): 51.

Wong O.H., Huang F. and Chiang A.K.S., Role of dendritic cell in the immune regulation of primary epstein-barr virus infection / Proceedings 12th International Congress of Immunology, Montreal. Montreal, 2004.

Yau T.O., Chan P.C.Y., Chan K.L., Lee M.F., Wong C.M., Fan S.T. and Ng I.O.L., Under-expression of HDPR1, a novel inhibitor of WNT/b-catenin signaling pathway, in hepatocellular carcinoma (Abstract), The 4th International Meeting on Hepatocellular Carcinoma: Eastern and Western Experiences, Hong Kong, 14-16 December 2004.